Assessment of the frequency dependence of acoustic properties on material, composition, and scatterer size of the medium

Assessment of the frequency dependence of acoustic properties on material, composition, and scatterer size of the medium
复制标题

评估声学特性对介质材料、成分和散射体尺寸的频率依赖性

DOI:
10.1007/s10396-022-01235-1
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发表时间:
2022
影响因子:
1.8
通讯作者:
Yamaguchi Tadashi
Yamaguchi Tadashi
中科院分区:
医学4区
文献类型:
--
作者:
Ino Mai;Yoshida Kenji;Hirata Shinnosuke;Ito Kazuyo;Yamaguchi Tadashi

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目的研究具有可控衰减特性的体模中声速和衰减系数的频率依赖性方法用超声评价SoS和衰减系数的频率依赖性(1-15 MHz)通过观察具有不同散射体尺寸、密度以及是否存在作为吸收介质的淡炼乳的多个幻影来进行。正常和脂肪模型大鼠肝脏进行了检查与相同protocol.ResultsThe幻影的结果表明,散射体密度和基础媒体的SoS的主导因素引起的SoS的变化。在SoS中未观察到频率依赖性。衰减系数的评估表明,当散射体与肝细胞一样小(即≤ 10 µm)时,频率依赖性主要受吸收衰减的影响。散射衰减也被观察到影响频率依赖性时,散射体是大的脂滴(即≤ 40 µm)。ConclusionAssuming一个一致的大小的主要散射体在评估介质中,频率依赖性的SoS和衰减系数可以提供洞察散射体密度和吸收和散射衰减的贡献。在更高频段(高达约50 MHz)的进一步研究有望推进高频超声的临床应用。
PurposeThe aim of this study was to elucidate the frequency dependence of the speed of sound (SoS) and attenuation coefficients in phantoms with controlled attenuation properties (scatterer density, scatterer size, absorption control material) and rat livers.MethodsThe frequency dependence of SoS and attenuation coefficients were evaluated with ultrasound (1–15 MHz) by observing multiple phantoms with different scatterer sizes, densities, and presence or absence of evaporated milk as absorbing media. Normal and fatty model rat livers were examined with the same protocol.ResultsThe phantom results revealed that the scatterer density and SoS of the base media were the dominant factors causing the changes in SoS. Frequency dependence was not observed in SoS. Assessment of the attenuation coefficient showed that the frequency dependence was mainly affected by absorption attenuation when the scatterer was as small as a hepatocyte (i.e. ≤ 10 µm). Scattering attenuation was also observed to affect frequency dependence when the scatterer was as large as lipid droplets (i.e. ≤ 40 µm).ConclusionAssuming a consistent size of the main scatterers in the evaluation medium, the frequency dependence of the SoS and attenuation coefficients may provide insight into the scatterer density and the contribution of absorption and scattering attenuation. Further studies in the higher frequency band (up to about 50 MHz) are expected to advance the clinical application of high-frequency ultrasound.
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发表时间: 2011-03
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DOI: --
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