Cytoskeletal dynamics: a view from the membrane.
Cytoskeletal dynamics: a view from the membrane.
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细胞骨架动力学:膜的视图。
DOI:
10.1083/jcb.201502062
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发表时间:
2015-05-11
期刊:
影响因子:
--
通讯作者:
Lee WL
中科院分区:
文献类型:
--
作者:
Bezanilla M;Gladfelter AS;Kovar DR;Lee WL
Many aspects of cytoskeletal assembly and dynamics can be recapitulated in vitro; yet, how the cytoskeleton integrates signals in vivo across cellular membranes is far less understood. Recent work has demonstrated that the membrane alone, or through membrane-associated proteins, can effect dynamic changes to the cytoskeleton, thereby impacting cell physiology. Having identified mechanistic links between membranes and the actin, microtubule, and septin cytoskeletons, these studies highlight the membrane’s central role in coordinating these cytoskeletal systems to carry out essential processes, such as endocytosis, spindle positioning, and cellular compartmentalization.
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DOI:
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