Dependence of ultrasound echo decorrelation on local tissue temperature during ex vivo radiofrequency ablation.

Dependence of ultrasound echo decorrelation on local tissue temperature during ex vivo radiofrequency ablation.
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DOI:
10.1088/0031-9155/61/6/2356
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发表时间:
2016-03-21
影响因子:
3.5
通讯作者:
Mast TD
Mast TD
中科院分区:
工程技术2区
文献类型:
--
作者:
Subramanian S;Schmidt DT;Rao MB;Mast TD

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This study investigates echo decorrelation imaging, an ultrasound method for thermal ablation monitoring. The effect of tissue temperature on the mapped echo decorrelation parameter was assessed in radiofrequency ablation experiments performed on ex vivo bovine liver tissue. Echo decorrelation maps were compared with corresponding tissue temperatures simulated using the finite element method. For both echo decorrelation imaging and integrated backscatter imaging, the mapped tissue parameters correlated significantly but weakly with local tissue temperature. Receiver operating characteristic (ROC) curves were used to assess the ability of echo decorrelation and integrated backscatter to predict tissue temperature greater than 40, 60, and 80°C. Significantly higher area under the ROC curve (AUROC) values were obtained for prediction of tissue temperatures greater than 40, 60, and 80°C using echo decorrelation imaging (AUROC = 0.871, 0.948 and 0.966) compared to integrated backscatter imaging (AUROC = 0.865, 0.877 and 0.832).
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