Construct validity of the PROMIS® sexual function and satisfaction measures in patients with cancer.

Construct validity of the PROMIS® sexual function and satisfaction measures in patients with cancer.
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DOI:
10.1186/1477-7525-11-40
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发表时间:
2013-03-11
影响因子:
3.6
通讯作者:
Weinfurt KP
Weinfurt KP
中科院分区:
医学3区
文献类型:
--
作者:
Flynn KE;Reeve BB;Lin L;Cyranowski JM;Bruner DW;Weinfurt KP

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利用来自癌症治疗或癌症治疗后患者的不同样本的数据,我们检查了患者报告结果测量信息系统性功能和满意度测量(PROMIS®SexFS)的核心域之间的域间和跨域相关性,以及来自概念相似的性功能测量,国际勃起功能指数和女性性功能指数的相应域。男性(N=389)和女性(N=430)从肿瘤登记处、肿瘤诊所和互联网小组中招募。使用PROMIS SexFS、国际勃起功能指数和女性性功能指数收集参与者自我报告的性功能。这些测量共有的领域包括对性活动的欲望/兴趣、润滑和阴道不适/疼痛(女性)、勃起功能(男性)、性高潮和满意度。我们检查了同一工具中不同领域之间的相关性(判别效度)和不同工具测量的相似领域之间的相关性(收敛效度)。男性的判别效度为0.38 - 0.73,女性为0.48 - 0.74,而男性的收敛效度为0.62 - 0.83,女性为0.71 - 0.92。正如预期的那样,趋同效度的相关性高于区别效度的相关性,只有一个例外(男性的性高潮)。在不同的癌症患者样本中,结构效度得到了收敛效度和区别效度的支持。对于可能或可能没有性功能障碍的癌症患者,PROMIS SexFS测量提供了性功能和满意度关键领域的综合评估。
With data from a diverse sample of patients either in treatment for cancer or post-treatment for cancer, we examine inter-domain and cross-domain correlations among the core domains of the Patient-Reported Outcomes Measurement Information System Sexual Function and Satisfaction measures (PROMIS® SexFS) and the corresponding domains from conceptually-similar measures of sexual function, the International Index of Erectile Function and the Female Sexual Function Index. Men (N=389) and women (N=430) were recruited from a tumor registry, oncology clinics, and an internet panel. The PROMIS SexFS, International Index of Erectile Function, and Female Sexual Function Index were used to collect participants’ self-reported sexual function. The domains shared among the measures include desire/interest in sexual activity, lubrication and vaginal discomfort/pain (women), erectile function (men), orgasm, and satisfaction. We examined correlations among different domains within the same instrument (discriminant validity) and correlations among similar domains measured by different instruments (convergent validity). Correlations demonstrating discriminant validity ranged from 0.38 to 0.73 for men and 0.48 to 0.74 for women, while correlations demonstrating convergent validity ranged from 0.62 to 0.83 for men and 0.71 to 0.92 for women. As expected, correlations demonstrating convergent validity were higher than correlations demonstrating discriminant validity, with one exception (orgasm for men). Construct validity was supported by convergent and discriminant validity in a diverse sample of patients with cancer. For patients with cancer who may or may not have sexual dysfunction, the PROMIS SexFS measures provide a comprehensive assessment of key domains of sexual function and satisfaction.
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