Correlates and clinical implications of tic suppressibility.

Correlates and clinical implications of tic suppressibility.
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抽动抑制性的相关因素及临床意义。

DOI:
10.1007/s40474-021-00230-4
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发表时间:
2021-06
影响因子:
2
通讯作者:
Black KJ
Black KJ
中科院分区:
其他
文献类型:
--
作者:
Ueda K;Kim S;Greene DJ;Black KJ

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抽动障碍在儿科人群中很常见,并通过抽动抑制与其他运动障碍区分开来。了解抽动抑制的机制可能为抽动障碍的病理生理学提供新的见解。本文重点介绍抽动抑制的临床现象和神经元相关性。最近的研究表明,抽搐抑制存在于儿童抽搐发作后不久。此外,那些能够更好地抑制抽搐的人有更好的抽搐结果。内感受性意识和自动动作抑制可能参与抽动抑制。我们阐述了抽搐抑制的潜在机制及其临床相关性和意义。新的概念,如内感受意识和行动抑制可能有助于解释抽动障碍。进一步的研究将有助于填补剩余的知识空白。
Tic disorders are common in the pediatric population and are differentiated from other movement disorders by tic suppressibility. Understanding the mechanism of tic suppression may provide new insights to the pathophysiology of tic disorders. This article highlights clinical phenomenology and neuronal correlates of tic suppressibility. Recent studies suggest that tic suppressibility exists in children shortly after onset of their tics. Moreover, those who are better able to suppress their tics have better tic outcomes. Interoceptive awareness and automatic action inhibition may be involved in tic suppression. We illustrate a possible underlying mechanism of tic suppressibility and its clinical correlations and implications. New concepts such as interoceptive awareness and action inhibition may help explain tic disorders. Further study will be useful to fill remaining knowledge gaps.
DOI: 10.1111/jnp.12089
发表时间: 2016-03
影响因子: 2.2
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