Mortality modeling: A review

Mortality modeling: A review
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死亡率建模:回顾

DOI:
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发表时间:
2000
期刊:
影响因子:
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通讯作者:
A. Begun
A. Begun
中科院分区:
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文献类型:
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作者:
A. Yashin;I. Iachine;A. Begun

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从衰老的生物学指标来看生存问题,已经产生了各种死亡率模型,我们在这里回顾其中一些模型。最著名的模型是Strehler和Mildvan的模型,它将死亡力与生物体补偿压力的能力联系起来,以及Sacher和Trucco的模型,它描述了稳态力在形成特定年龄死亡模式中所起的作用。在老化研究的纵向数据的分析,现在纳入了异质性和脆弱性的概念,以及在“修复能力”的变化;的有机体。此外,人们现在正在关注进化理论和衰老模型。这些模型和进一步研究的方向进行了讨论。
Looking at survival in terms of biological indicators of aging has given rise to various models of mortality, some of which we review here. The most notable models are that of Strehler and Mildvan, which relates the force of mortality to the ability of organisms to compensate for stress, and that of Sacher and Trucco, which describes the role played by homeostatic forces in shaping the age‐specific pattern of mortality. The analysis of longitudinal data in aging studies now incorporates the notions of heterogeneity and frailty, as well as that of changes in the “repair capacity”; of organisms. Furthermore, attention is now being paid to evolutionary theory and to models of senescence. These models and directions for further research are discussed.
异质人群的死亡率和老龄化:具有观察和未观察变量的随机过程模型。
DOI: 10.1016/0040-5809(85)90008-5
发表时间: 1985
影响因子: 1.4
作者:
Yashin,AI;Manton,KG;Vaupel,JW
通讯作者: Vaupel,JW
DOI: 10.1126/science.1411541
发表时间: 1992-10-16
期刊: SCIENCE
影响因子: 56.9
作者:
CURTSINGER, JW;FUKUI, HH;VAUPEL, JW
通讯作者: VAUPEL, JW
DOI: 10.1126/science.1411540
发表时间: 1992-10-16
期刊: SCIENCE
影响因子: 56.9
作者:
CAREY, JR;LIEDO, P;VAUPEL, JW
通讯作者: VAUPEL, JW