Posttraumatic stress disorder (PTSD) in survivors of Hodgkin's lymphoma: prevalence of PTSD and partial PTSD compared with sibling controls.
Posttraumatic stress disorder (PTSD) in survivors of Hodgkin's lymphoma: prevalence of PTSD and partial PTSD compared with sibling controls.
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DOI：
10.1002/pon.2109
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发表时间：
2013-02
期刊：
影响因子：
3.6
通讯作者：
Recklitis, Christopher J.
中科院分区：
文献类型：
--
作者：
Varela, Veronica Sanchez;Ng, Andrea;Mauch, Peter;Recklitis, Christopher J.
PTSD的研究记录了相当大比例的癌症幸存者报告了严重的创伤后应激（PTS）症状，即使他们不符合完整的诊断标准。然而，很少有研究直接研究这些“部分PTSD”症状在幸存者中的临床意义。本研究旨在调查HL长期幸存者队列中PTSD症状的患病率，并通过评估继发于亚阈值精神病学的功能损害来探讨部分PTSD现象的临床相关性。105名HL幸存者和101名同胞对照者完成了创伤后诊断量表（PDS）。参与时的存活者年龄范围为24-71岁，诊断时的年龄范围为6-61岁，自诊断以来的中位时间为16年（范围= 7 - 34）。HL幸存者的PTSD患病率（13%）与兄弟姐妹对照组（6.9%，p = 0.098）相比并不显著更高。然而，与兄弟姐妹（17.8%，p = 0.004）相比，幸存者（35.2%）符合部分PTSD标准的比例显着更大。此外，大多数部分PTSD的幸存者（86.5%）报告经历了一些与这些PTS症状相关的功能障碍。大量HL幸存者出现严重到足以导致功能损害的PTS症状。这些发现强调了未来研究的重要性，详细说明部分PTSD幸存者的心理和功能结果，以及仔细的临床实践，评估继发于部分PTSD的功能障碍，男性和女性幸存者，即使在治疗完成后数年。
Studies of PTSD document a significant proportion of cancer survivors reporting severe posttraumatic stress (PTS) symptoms, even when they do not meet full diagnostic criteria. However, few studies have directly examined the clinical significance of these “partial-PTSD” symptoms in survivors. This study aimed to investigate the prevalence of PTSD symptoms in a cohort of long-term survivors of HL, and to explore the clinical relevance of the partial-PTSD phenomenon by assessing impairment of function secondary to sub-threshold symptomatology. The Posttraumatic Diagnostic Scale (PDS), was completed by 105 HL survivors and 101 sibling controls. Survivors age at time of participation ranged from 24–71 years, age at time of diagnosis ranged from 6–61 years, and the median time since diagnosis was 16 years (range = 7 – 34). PTSD prevalence was not significantly higher in HL survivors (13%) compared to sibling controls (6.9%, p = .098). However, a significantly larger proportion of survivors (35.2%) met criteria for partial-PTSD compared to siblings (17.8%, p = .004). Moreover, the majority of the survivors with partial-PTSD (86.5%) reported experiencing some functional impairment related to these PTS symptoms. A significant number of HL survivors experience PTS symptoms severe enough to result in functional impairment. These findings underscore the importance of future research detailing the psychological and functional outcomes in survivors with partial-PTSD, and of careful clinical practice that assesses for functional impairment secondary to partial-PTSD symptomatology, in male and female survivors, even years after completion of therapy.
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影响因子：
50.5
作者：
Ng, AK;Li, S;Diller, L
通讯作者：
Diller, L
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作者：
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影响因子：
3.3
作者：
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通讯作者：
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作者：
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通讯作者：
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