The effects of FreeSurfer version, workstation type, and Macintosh operating system version on anatomical volume and cortical thickness measurements.
The effects of FreeSurfer version, workstation type, and Macintosh operating system version on anatomical volume and cortical thickness measurements.
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DOI：
10.1371/journal.pone.0038234
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发表时间：
2012
期刊：
影响因子：
3.7
通讯作者：
Marcelis M
中科院分区：
文献类型：
--
作者：
Gronenschild EH;Habets P;Jacobs HI;Mengelers R;Rozendaal N;van Os J;Marcelis M
FreeSurfer是一个流行的软件包，用于测量皮质厚度和神经解剖结构的体积。然而，很少有人知道在各种数据处理条件下的测量可靠性。使用一组30个解剖T1加权3 T MRI扫描，我们研究了FreeSurfer版本（v4.3.1、v4.5.0和v5.0.0）、工作站（Macintosh和Hewlett-Packard）和Macintosh操作系统版本（OSX 10.5和OSX 10.6）等数据处理变量的影响。FreeSurfer v5.0.0版与两个早期版本之间存在显著差异。这些差异平均为8.8±6.6%（范围1.3-64.0%）（体积）和2.8±1.3%（1.1-7.7%）（皮质厚度）。在Macintosh和Hewlett-Packard工作站之间以及OSX 10.5和OSX 10.6之间检测到大约两个较小的差异。观察到的差异在幅度上与准确性评价和神经退行性研究中报告的效应量相似。主要结论是，在正在进行的研究中，不鼓励用户更新到FreeSurfer或操作系统的新主要版本，或者在不重复分析的情况下切换到不同类型的工作站;因此，结果为FreeSurfer开发人员多年来提出的连续建议提供了定量支持。此外，鉴于大的和显着的跨版本的差异，它的结论是，FreeSurfer的准确性的正式评估是可取的。
FreeSurfer is a popular software package to measure cortical thickness and volume of neuroanatomical structures. However, little if any is known about measurement reliability across various data processing conditions. Using a set of 30 anatomical T1-weighted 3T MRI scans, we investigated the effects of data processing variables such as FreeSurfer version (v4.3.1, v4.5.0, and v5.0.0), workstation (Macintosh and Hewlett-Packard), and Macintosh operating system version (OSX 10.5 and OSX 10.6). Significant differences were revealed between FreeSurfer version v5.0.0 and the two earlier versions. These differences were on average 8.8±6.6% (range 1.3–64.0%) (volume) and 2.8±1.3% (1.1–7.7%) (cortical thickness). About a factor two smaller differences were detected between Macintosh and Hewlett-Packard workstations and between OSX 10.5 and OSX 10.6. The observed differences are similar in magnitude as effect sizes reported in accuracy evaluations and neurodegenerative studies. The main conclusion is that in the context of an ongoing study, users are discouraged to update to a new major release of either FreeSurfer or operating system or to switch to a different type of workstation without repeating the analysis; results thus give a quantitative support to successive recommendations stated by FreeSurfer developers over the years. Moreover, in view of the large and significant cross-version differences, it is concluded that formal assessment of the accuracy of FreeSurfer is desirable.
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影响因子：
5.7
作者：
Jovicich J;Czanner S;Han X;Salat D;van der Kouwe A;Quinn B;Pacheco J;Albert M;Killiany R;Blacker D;Maguire P;Rosas D;Makris N;Gollub R;Dale A;Dickerson BC;Fischl B
通讯作者：
Fischl B
影响因子：
5.7
作者：
Fischl, B;Sereno, MI;Dale, AM
通讯作者：
Dale, AM
影响因子：
3.7
作者：
Dickerson, Bradford C.;Bakkour, Akram;Salat, David H.;Feczko, Eric;Pacheco, Jenni;Greve, Douglas N.;Grodstein, Fran;Wright, Christopher I.;Blacker, Deborah;Rosas, H. Diana;Sperling, Reisa A.;Atri, Alireza;Growdon, John H.;Hyman, Bradley T.;Morris, John C.;Fischl, Bruce;Buckner, Randy L.
通讯作者：
Buckner, Randy L.
影响因子：
4.8
作者：
Morey, Rajendra A.;Selgrade, Elizabeth S.;Wagner, Henry Ryan, II;Huettel, Scott A.;Wang, Lihong;McCarthy, Gregory
通讯作者：
McCarthy, Gregory
DOI：
10.1111/j.2517-6161.1995.tb02031.x
发表时间：
1995-01-01
影响因子：
5.8
作者：
BENJAMINI, Y;HOCHBERG, Y
通讯作者：
HOCHBERG, Y