The spike-timing dependence of plasticity.
The spike-timing dependence of plasticity.
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DOI:
10.1016/j.neuron.2012.08.001
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发表时间:
2012-08-23
期刊:
影响因子:
16.2
通讯作者:
Feldman DE
中科院分区:
文献类型:
--
作者:
Feldman DE
In spike timing-dependent plasticity (STDP), the order and precise temporal interval between presynaptic and postsynaptic spikes determine the sign and magnitude of long-term potentiation (LTP) or depression (LTD). STDP is widely utilized in models of circuit-level plasticity, development, and learning. However, spike timing is just one of several factors (including firing rate, synaptic cooperativity, and depolarization) that govern plasticity induction, and its relative importance varies across synapses and activity regimes. This review summarizes the forms, cellular mechanisms, and prevalence of STDP, and evaluates the evidence that spike timing is an important determinant of plasticity in vivo.
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DOI:
10.1523/jneurosci.4429-08.2008
发表时间:
2008-12-10
期刊:
The Journal of neuroscience : the official journal of the Society for Neuroscience
影响因子:
--
作者:
Dahmen JC;Hartley DE;King AJ
通讯作者:
King AJ
影响因子:
2.5
作者:
Farries, Michael A.;Fairhall, Adrienne L.
通讯作者:
Fairhall, Adrienne L.
影响因子:
25
作者:
Clopath, Claudia;Buesing, Lars;Gerstner, Wulfram
通讯作者:
Gerstner, Wulfram
影响因子:
13.9
作者:
Feldman DE
通讯作者:
Feldman DE
影响因子:
25
作者:
Bissière, S;Humeau, Y;Lüthi, A
通讯作者:
Lüthi, A