CDPKs in immune and stress signaling.

CDPKs in immune and stress signaling.
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DOI:
10.1016/j.tplants.2012.08.008
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发表时间:
2013-01
影响因子:
20.5
通讯作者:
Sheen, Jen
Sheen, Jen
中科院分区:
生物学1区
文献类型:
--
作者:
Boudsocq, Marie;Sheen, Jen

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钙离子(Ca2+)长期以来被认为是植物免疫和应激反应中一种保守的第二信使和主要介导因子。Ca2+信号是如何被感知并传递到各种初级和全局信号事件中的,在很大程度上仍然未知。对植物特有的钙依赖蛋白激酶(CDPKs)多基因家族的综合分析正在揭示Ca2+信号传导的分子、细胞和遗传机制。CDPKs表现出重叠和不同的表达模式、亚细胞定位、底物特异性和Ca2+敏感性,在酶、通道和转录因子的激活和抑制中发挥多种作用。在此,我们综述了CDPKs在复杂的免疫和应激信号网络中的多方面功能的最新进展,包括氧化爆发、气孔运动、激素信号传导和基因调控。
Ca2+ has long been recognized as a conserved second messenger and principal mediator in plant immune and stress responses. How Ca2+ signals are sensed and relayed into diverse primary and global signaling events is still largely unknown. Comprehensive analyses of the plant-specific multigene family of Ca2+-dependent protein kinases (CDPKs) are unraveling the molecular, cellular and genetic mechanisms of Ca2+ signaling. CDPKs, which exhibit overlapping and distinct expression patterns, sub-cellular localizations, substrate specificities and Ca2+ sensitivities, play versatile roles in the activation and repression of enzymes, channels and transcription factors. Here, we review the recent advances on the multifaceted functions of CDPKs in the complex immune and stress signaling networks, including oxidative burst, stomatal movements, hormonal signaling and gene regulation.
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