Do rates of mental disorders and existential distress among advanced stage cancer patients increase as death approaches?
Do rates of mental disorders and existential distress among advanced stage cancer patients increase as death approaches?
复制标题
DOI：
10.1002/pon.1371
复制
发表时间：
2009-01
期刊：
影响因子：
3.6
通讯作者：
Prigerson, Holly G.
中科院分区：
文献类型：
--
作者：
Lichtenthall, Wendy G.;Nilsson, Matthew;Zhang, Baohui;Trice, Elizabeth D.;Kissane, David W.;Breitbart, William;Prigerson, Holly G.
关键词：
确定精神障碍的患病率和相关因素是否随着晚期癌症患者接近死亡而增加。作为晚期癌症患者多中心、纵向、前瞻性队列研究的一部分，来自289名患者的基线、横断面数据，这些患者在死亡前接受了评估。使用DSM-IV轴I障碍（SCID-I）的结构化临床访谈对重度抑郁症、广泛性焦虑症、惊恐障碍和创伤后应激障碍进行评估。其他检查的因素包括存在的幸福感，病人对他们的疾病的悲伤，身体症状负担，绝症承认，平静，和希望生存或死亡。接近死亡与精神障碍的发生率无关。接近死亡的患者表现出更大的生存压力和身体症状负担，更有可能承认患有绝症，更有可能报告死亡愿望增加。结果并不支持抑郁症和焦虑症的患病率随着死亡的临近而增加的常见临床假设。然而，患者的身体痛苦程度，对绝症的承认，以及死亡的愿望，可能反映了接受死亡，随着死亡的临近而增加。需要进行纵向研究，以确认患者接近死亡时精神障碍发生率的个体变化。
To determine if the prevalence of mental disorders and related factors increase as advanced cancer patients get closer to death. Baseline, cross-sectional data from 289 patients who were assessed prior to their death as part of a multi-site, longitudinal, prospective cohort study of advanced cancer patients. Major Depressive Disorder, Generalized Anxiety Disorder, Panic Disorder, and Posttraumatic Stress Disorder were assessed using the Structured Clinical Interview for the DSM-IV Axis I Disorders (SCID-I). Other factors examined included existential well-being, patient grief about their illness, physical symptom burden, terminal illness acknowledgment, peacefulness, and the wish to live or die. Closeness to death was not associated with higher rates of mental disorders. Patients closer to death exhibited increased existential distress and physical symptom burden, were more likely to acknowledge being terminally ill, and were more likely to report an increased wish to die. Results do not provide support for the common clinical assumption that the prevalence of depressive and anxiety disorders increases as death nears. However, patients' level of physical distress, acknowledgment of terminal illness, and wish to die, possibly reflecting acceptance of dying, increased as death approached. Longitudinal studies are needed to confirm individual changes in rates of mental disorder as patients approach death.
登录
查看更多内容
影响因子：
7.6
作者：
BARON, RM;KENNY, DA
通讯作者：
KENNY, DA
影响因子：
4.4
作者：
Hinton, J
通讯作者：
Hinton, J
影响因子：
120.7
作者：
DEROGATIS, LR;MORROW, GR;CARNICKE, CLM
通讯作者：
CARNICKE, CLM
DOI：
10.1111/j.1440-1614.2004.01358.x
发表时间：
2004-05-01
影响因子：
4.6
作者：
Kissane, DW;Grabsch, B;Smith, GC
通讯作者：
Smith, GC
影响因子：
4.4
作者：
Chen, ML;Chang, HK
通讯作者：
Chang, HK