Social isolation and loneliness as risk factors for the progression of frailty: the English Longitudinal Study of Ageing.

Social isolation and loneliness as risk factors for the progression of frailty: the English Longitudinal Study of Ageing.
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DOI:
10.1093/ageing/afx188
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发表时间:
2018-05-01
期刊:
影响因子:
6.7
通讯作者:
Cooper C
Cooper C
中科院分区:
医学1区
文献类型:
--
作者:
Gale CR;Westbury L;Cooper C

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孤独和社会孤立一直与老年人的死亡率和功能衰退有关。我们调查了孤独或社交孤立是否与虚弱的进展有关。参与者是来自英国老龄化纵向研究的2,817名60岁的≥。在第2波时使用修订的加州大学洛杉矶分校量表(简称)评估孤独感。第二波的社会隔离得分来自独居、与朋友、家人和孩子联系的频率以及参与社会组织的数据。通过在第2和第4波身体虚弱的Fred表型以及在第2-5波的脆弱指数来评估脆弱。高水平的孤独与大约4年后变得身体虚弱或虚弱前的风险增加相关:在基线时,调整了年龄、性别、虚弱程度和其他潜在混杂因素的相对风险比(95%CI)为1.74(1.29,2.34),虚弱为1.85(1.14,2.99)。在平均6年的时间里,高度的孤独感与脆弱指数的变化无关--脆弱指数是一种衡量一般状况的广泛指标。在整个样本中,社交孤立与身体虚弱或前期虚弱的风险之间没有关联,但高度的社交孤立与男性身体虚弱的风险增加有关。社会孤立与脆弱指数的变化无关。经历高度孤独的老年人身体虚弱的风险增加。
loneliness and social isolation have been associated with mortality and with functional decline in older people. We investigated whether loneliness or social isolation are associated with progression of frailty. participants were 2,817 people aged ≥60 from the English Longitudinal Study of Ageing. Loneliness was assessed at Wave 2 using the Revised UCLA scale (short version). A social isolation score at Wave 2 was derived from data on living alone, frequency of contact with friends, family and children, and participation in social organisations. Frailty was assessed by the Fried phenotype of physical frailty at Waves 2 and 4, and by a frailty index at Waves 2–5. high levels of loneliness were associated with an increased risk of becoming physically frail or pre-frail around 4 years later: relative risk ratios (95% CI), adjusted for age, sex, level of frailty and other potential confounding factors at baseline were 1.74 (1.29, 2.34) for pre-frailty, and 1.85 (1.14, 2.99) for frailty. High levels of loneliness were not associated with change in the frailty index—a broadly based measure of general condition—over a mean period of 6 years. In the sample as a whole, there was no association between social isolation and risk of becoming physically frail or pre-frail, but high social isolation was associated with increased risk of becoming physically frail in men. Social isolation was not associated with change in the frailty index. older people who experience high levels of loneliness are at increased risk of becoming physically frail.
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