Risk of respiratory, gastrointestinal, and constitutional health symptoms: A cross-sectional study of Texas adolescent and young adult nicotine and marijuana vapers.

Risk of respiratory, gastrointestinal, and constitutional health symptoms: A cross-sectional study of Texas adolescent and young adult nicotine and marijuana vapers.
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DOI:
10.1016/j.ypmed.2022.107057
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发表时间:
2022-06
影响因子:
5.1
通讯作者:
Harrell, Melissa B.
Harrell, Melissa B.
中科院分区:
医学2区
文献类型:
--
作者:
Case, Kathleen R.;Clendennen, Stephanie L.;Tsevat, Joel;Harrell, Melissa B.

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调查青少年和年轻人吸电子烟对健康影响的观察性研究有限。本研究旨在描述和检查电子烟使用者类别(从不使用者、只使用大麻、只使用尼古丁和双重使用者)对健康症状的风险。健康症状包括呼吸道、胃肠道和体质问题。这项横断面研究分析了2020年秋季德克萨斯州青少年烟草和营销监测系统第12波(n = 2389)的数据。卡方、单因素方差分析(ANOVA)和多变量逻辑回归分析检验了过去30天电子烟使用者类别与15种健康症状(如咳嗽、恶心、呕吐、发烧)之间的关系。对于总症状,双烟者报告的平均值最高(2.76[标准差= 3.17]),其次是纯尼古丁吸烟者(2.47[2.89]),纯大麻吸烟者(1.94[2.60]),从不吸烟者(1.56[2.31]),p < 0.001。与从不吸烟者相比,双烟吸烟者和纯尼古丁吸烟者出现呼吸道症状的几率明显更高(调整后的比值比[AOR] = 2.35, 95%可信区间[CI]: 1.30, 4.25; AOR = 1.86, 95% CI: 1.22, 2.81)。纯大麻(AOR = 2.41, 95% CI: 1.53, 3.79)、纯尼古丁(AOR = 2.03, 95% CI: 1.38, 2.99)和双吸者(AOR = 2.03, 95% CI: 1.15, 3.57)与从不吸食者相比,出现胃肠道症状的几率明显更高。与从不使用电子烟的人相比,双烟者出现体质症状的几率明显更高(AOR = 1.92, 95% CI: 1.10, 3.34)。这项研究独特地强调了电子烟引起胃肠道症状的风险。未来的研究和临床实践应该监测这些症状的发生,并探索电子烟与健康症状之间联系的潜在机制,如特定的香料或化学物质。
Observational studies investigating the health consequences of vaping among youth and young adults are limited. This study aimed to describe and examine the risk for health symptoms by vape user category (never users, marijuana only, nicotine only, and dual users). Health symptoms included adverse respiratory, gastrointestinal, and constitutional problems. This cross-sectional study analyzed data from Fall 2020, Wave 12 (n = 2389) of the Texas Adolescent Tobacco and Marketing Surveillance System. Chi-square, one-way analysis of variance (ANOVA), and multivariable logistic regression analyses examined the associations between past 30-day vape user category and 15 health symptoms (e.g., coughing, nausea, vomiting, fever). For total symptoms, dual vapers reported the highest mean (2.76[standard deviation = 3.17]), followed by nicotine-only vapers (2.47 [2.89]), marijuana-only vapers (1.94[2.60]), and never users (1.56[2.31]), p < .001. Dual vapers and nicotine-only vapers had significantly higher odds of experiencing respiratory symptoms as compared with never users (adjusted odds ratios [AORs] = 2.35, 95% confidence interval [CI]: 1.30, 4.25; AOR = 1.86, 95% CI: 1.22, 2.81, respectively). Marijuana-only (AOR = 2.41, 95% CI: 1.53, 3.79), nicotine-only (AOR = 2.03, 95% CI: 1.38, 2.99), and dual vapers (AOR = 2.03, 95% CI: 1.15, 3.57) had significantly higher odds of gastrointestinal symptoms compared with never users. Dual vapers had significantly higher odds of experiencing constitutional symptoms as compared to never users (AOR = 1.92, 95% CI: 1.10, 3.34). This study uniquely highlights the risk for gastrointestinal symptoms from vaping. Future research and clinical practice should monitor the occurrence of these symptoms and explore potential mechanisms, such as specific flavorings or chemicals, for the link between vaping and health symptoms.
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