Auditory brainstem development and plasticity.
Auditory brainstem development and plasticity.
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DOI:
10.1016/j.cophys.2020.07.002
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发表时间:
2020-12
影响因子:
2.5
通讯作者:
Rubio ME
中科院分区:
文献类型:
--
作者:
Rubio ME
During development and adulthood, the normal activity of the auditory nerve plays a critical role in the maintenance of both fundamental structural, molecular, and functional parameters of auditory nerve synapses, and the postsynaptic excitatory or inhibitory neurons within the cochlear nucleus (CN). In addition, normal activity within the synaptic circuits of the CN is key to developing and maintaining appropriate synapse connectivity as well as the initiation of binaural sound processing in the superior olivary complex (SOC). Development plays a critical role in the proper neuronal connectivity and establishes a topographic map along the entire auditory pathway. Furthermore, evidence shows that neurons and synaptic circuits in the auditory brainstem are not hard-wired, but instead are plastic in response to hearing deficits. Whether this plasticity in response to hearing loss is compensatory or pathological is still unknown.
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DOI:
10.1523/jneurosci.1848-05.2005
发表时间:
2005-09-14
期刊:
The Journal of neuroscience : the official journal of the Society for Neuroscience
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2014-07
期刊:
The European journal of neuroscience
影响因子:
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