Enzyme-linked immunosorbent assay for the detection of antibodies to nutritionally variant streptococci in patients with endocarditis.
Enzyme-linked immunosorbent assay for the detection of antibodies to nutritionally variant streptococci in patients with endocarditis.
复制标题
用于检测心内膜炎患者营养变异链球菌抗体的酶联免疫吸附测定。
DOI:
10.1093/infdis/153.1.116
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发表时间:
1986
期刊:
影响因子:
--
通讯作者:
Roberts,RB
中科院分区:
文献类型:
--
作者:
vandeRijn,I;George,M;Bouvet,A;Roberts,RB
The viridans streptococci are responsible for 50%–55% of microbial endocarditis. Among these varied species, the nutritionally variant streptococci (NVS) have recently been associated with culture-negative endocarditis and are responsible for 5%–10% of all streptococcal endocarditis. The isolation and identification of these bacteria has been hampered by the extremely fastidious nature of their growth requirements as well as by their slow growth rate. In addition, their antibiotic sensitivity varies greatly, a characteristic leading to a higher rate of morbidity and mortality than is found in patients with non-NVS endocarditis. For these reasons sera from patients with NVS endocarditis were examined for antibodies to the NVS serotype I antigen by using an enzyme-linked immunosorbent assay. Seventy-four percent of patients with NVS endocarditis had elevated titers to this antigen. None of the sera from controls and only 6.7% of the sera from patients with non-NVS streptococcal endocarditis showed increased titers. These results indicate that antibody to the NVS serotype I antigen can serve as a marker for NVS endocarditis.
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DOI:
--
发表时间:
1980
期刊:
影响因子:
--
作者:
S. Hamada;J. Mizuno;S. Kotani;M. Torii
通讯作者:
M. Torii
影响因子:
56.9
作者:
B. Rosan
通讯作者:
B. Rosan
影响因子:
3.1
作者:
R. B. Clark;R. Gordon;E. Bottone;M. Reitano
通讯作者:
M. Reitano
DOI:
--
发表时间:
1983
期刊:
影响因子:
--
作者:
N. Harboe;P. J. Svendsen
通讯作者:
P. J. Svendsen
DOI:
10.1084/jem.141.5.990
发表时间:
1975-05-01
期刊:
The Journal of experimental medicine
影响因子:
--
作者:
Ofek I;Beachey EH;Jefferson W;Campbell GL
通讯作者:
Campbell GL