Three measures of forest fire smoke exposure and their associations with respiratory and cardiovascular health outcomes in a population-based cohort.
Three measures of forest fire smoke exposure and their associations with respiratory and cardiovascular health outcomes in a population-based cohort.
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DOI：
10.1289/ehp.1002288
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发表时间：
2011-09
影响因子：
10.4
通讯作者：
Kennedy SM
中科院分区：
文献类型：
--
作者：
Henderson SB;Brauer M;Macnab YC;Kennedy SM
背景：2003年夏天，加拿大不列颠哥伦比亚省发生了多起火灾。目的：在为期92天的研究期间（2003年7月1日至9月30日），我们研究了呼吸和心血管医生就诊与住院之间的关系，以及三种烟雾暴露措施。方法：从行政数据中确定了一个以人口为基础的281,711名居民队列。根据六个调节锥形元件振荡微平衡（TEOM）空气质量监测仪的空气动力学直径≤10 μm的颗粒物（PM） （PM10）的总测量值，为研究运行的CALPUFF分散模型的烟雾相关PM10，以及卫星图像中可见的烟雾暴露度量值，为每个受试者分配了空间特定的每日暴露估计值。使用重复测量的逻辑回归来估计与每个结果的关联。结果：基于teom测量PM10的平均（±SD）暴露量为29±31 μg/m3，四分位数范围为14 ~ 31 μg/m3。TEOM、烟雾和CALPUFF指标之间的相关性为中等（0.37-0.76）。基于teom的PM10增加30 μg/m3的优势比（or）在所有呼吸内科就诊中为1.05[95%可信区间（CI）， 1.03-1.06]，在哮喘特异性就诊中为1.16 (95% CI, 1.09-1.23)，在呼吸内科住院患者中为1.15 （95% CI, 1.00-1.29）。与心血管结局的关联基本为零。结论：总的来说，我们发现teom测量的PM10的增加与呼吸内科医生就诊和住院的几率增加有关，但与心血管健康结果无关。表明火灾烟雾对呼吸结果影响的结果与先前的研究一致，心血管结果的无效结果也是如此。TEOM和其他指标之间的一些一致表明，独立于空气质量监测的暴露评估工具可能会进一步完善。
Background: During the summer of 2003 numerous fires burned in British Columbia, Canada. Objectives: We examined the associations between respiratory and cardiovascular physician visits and hospital admissions, and three measures of smoke exposure over a 92-day study period (1 July to 30 September 2003). Methods: A population-based cohort of 281,711 residents was identified from administrative data. Spatially specific daily exposure estimates were assigned to each subject based on total measurements of particulate matter (PM) ≤ 10 μm in aerodynamic diameter (PM10) from six regulatory tapered element oscillating microbalance (TEOM) air quality monitors, smoke-related PM10 from a CALPUFF dispersion model run for the study, and a SMOKE exposure metric for plumes visible in satellite images. Logistic regression with repeated measures was used to estimate associations with each outcome. Results: The mean (± SD) exposure based on TEOM-measured PM10 was 29 ± 31 μg/m3, with an interquartile range of 14–31 μg/m3. Correlations between the TEOM, smoke, and CALPUFF metrics were moderate (0.37–0.76). Odds ratios (ORs) for a 30-μg/m3 increase in TEOM-based PM10 were 1.05 [95% confidence interval (CI), 1.03–1.06] for all respiratory physician visits, 1.16 (95% CI, 1.09–1.23) for asthma-specific visits, and 1.15 (95% CI, 1.00–1.29) for respiratory hospital admissions. Associations with cardiovascular outcomes were largely null. Conclusions: Overall we found that increases in TEOM-measured PM10 were associated with increased odds of respiratory physician visits and hospital admissions, but not with cardiovascular health outcomes. Results indicating effects of fire smoke on respiratory outcomes are consistent with previous studies, as are the null results for cardiovascular outcomes. Some agreement between TEOM and the other metrics suggests that exposure assessment tools that are independent of air quality monitoring may be useful with further refinement.
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影响因子：
3.5
作者：
Sastry, N
通讯作者：
Sastry, N
影响因子：
37.8
作者：
Pope, CA;Burnett, RT;Godleski, JJ
通讯作者：
Godleski, JJ
影响因子：
4.9
作者：
Delfino RJ;Brummel S;Wu J;Stern H;Ostro B;Lipsett M;Winer A;Street DH;Zhang L;Tjoa T;Gillen DL
通讯作者：
Gillen DL
影响因子：
10.4
作者：
Dockery, DW
通讯作者：
Dockery, DW
影响因子：
24.3
作者：
Swiston, J. R.;Davidson, W.;van Eeden, S. F.
通讯作者：
van Eeden, S. F.