Advancing full length genome sequencing for human RNA viral pathogens.
Advancing full length genome sequencing for human RNA viral pathogens.
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DOI:
10.2217/17460794.4.1.47
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发表时间:
2009-01
期刊:
影响因子:
3.1
通讯作者:
Spiro D
中科院分区:
文献类型:
--
作者:
Djikeng A;Spiro D
In the face of numerous emerging and re-emerging viral threats, large-scale genome sequencing efforts are underway to monitor viral evolution in real-time. To fully appreciate the mechanisms of viral adaptation and evolution, and to also develop reagents and resources for a better molecular diagnosis of emerging and re-emerging viral infections, there has been an increasing effort toward producing full length viral genome sequences. To date, high-throughput platforms have been developed using traditional Sanger-based sequencing and there are currently prospects to apply next generation sequencing methods to develop an ultra high-throughput strategy for viral genome sequencing and analysis.
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