Separate spatial and temporal frequency tuning to visual motion in human MT+ measured with ECoG.

Separate spatial and temporal frequency tuning to visual motion in human MT+ measured with ECoG.
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DOI:
10.1002/hbm.23361
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发表时间:
2017-01
影响因子:
4.8
通讯作者:
Petridou N
Petridou N
中科院分区:
医学2区
文献类型:
--
作者:
Gaglianese A;Harvey BM;Vansteensel MJ;Dumoulin SO;Ramsey NF;Petridou N

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人类中时复合体(Middle Temporal Complex,hMT+)在视觉刺激中对运动方向和速度的处理和检测具有重要的生物学意义。在这里,我们描述了hMT+中的神经元群体如何编码移动视觉刺激的速度。我们评估了人类颅内皮层电图(ECoG)引起的方波飞镖运动刺激与不同的空间和时间频率的反应,以调查是否hMT+神经元群体编码的刺激速度直接,或者他们是否单独的运动到其空间和时间的组成部分。我们从ECoG响应中提取了两个分量:1)高频带(HFB:65-95 Hz)中的功率,作为神经元群体尖峰活动的量度,以及2)跟随刺激的对比度反转(SCR响应)的频率的特定频谱分量。我们的研究结果表明,HFB神经元群体对视觉运动刺激的反应表现出明显的和独立的选择性的空间和时间频率的视觉刺激,而不是直接的速度调谐。SCR反应没有编码的速度或时空频率的视觉刺激。我们的结论是,在hMT+中测量的神经元群体不直接调谐到刺激速度,而是通过单独和独立的空间和时间频率调谐来编码速度。
The human Middle Temporal complex (hMT+) has a crucial biological relevance for the processing and detection of direction and speed of motion in visual stimuli. Here, we characterized how neuronal populations in hMT+ encode the speed of moving visual stimuli. We evaluated human intracranial electrocorticography (ECoG) responses elicited by square-wave dartboard moving stimuli with different spatial and temporal frequency to investigate whether hMT+ neuronal populations encode the stimulus speed directly, or whether they separate motion into its spatial and temporal components. We extracted two components from the ECoG responses: 1) the power in the high-frequency band (HFB: 65–95 Hz) as a measure of the neuronal population spiking activity and 2) a specific spectral component that followed the frequency of the stimulus’s contrast reversals (SCR responses). Our results revealed that HFB neuronal population responses to visual motion stimuli exhibit distinct and independent selectivity for spatial and temporal frequencies of the visual stimuli rather than direct speed tuning. The SCR responses did not encode the speed or the spatiotemporal frequency of the visual stimuli. We conclude that the neuronal populations measured in hMT+ are not directly tuned to stimulus speed, but instead encode speed through separate and independent spatial and temporal frequency tuning.
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