High Contrast Reflectance Imaging of Enamel Demineralization and Remineralization at 1950-nm for the Assessment of Lesion Activity.
High Contrast Reflectance Imaging of Enamel Demineralization and Remineralization at 1950-nm for the Assessment of Lesion Activity.
复制标题
在1950-nm处釉质脱矿和再矿化的高对比度反射成像用于评估病变活动。
DOI：
10.1002/lsm.23371
复制
发表时间：
2021-09
影响因子：
2.4
通讯作者：
Fried D
中科院分区：
文献类型：
--
作者：
Fried WA;Abdelaziz M;Darling CL;Fried D
先前的研究表明，在空气干燥过程中，龋病变漫反射的大变化可以用来评估病变的活动性。最大的变化发生在短波长红外（SWIR）波长，与高吸水性一致。在SWIR中，最强的吸水率发生在1950-nm处。在本研究中，我们测量了不同矿化程度的模拟病变在1500 - 2340 nm和1950-nm处的反射率变化，并对样品进行了空气干燥。20个牛牙釉质表面各有5个治疗窗口，暴露于两种脱矿/再矿化方案中，以产生不同深度，严重程度和矿物梯度的模拟病变。采用长通滤光片的增程钨卤灯（1500 - 2340 nm）和以1950-nm吸水带峰附近为中心的宽带ASE光源作为光源，采用增程InGaAs相机（1000-2340-nm）在空气干燥过程中获取反射光图像。还使用数字显微镜、偏振光显微镜（PLM）、光学相干断层扫描（OCT）和横向显微放射照相（TMR）评估病变。在两个模型中，两个波长范围都显示出极高的病变对比度（> 0.9）。与1500 - 2340 nm波长范围相比，所有完整病变窗口的1950 nm宽带光源的对比度变化（ΔI）明显更高。1950-nm的SWIR光产生极高的脱矿对比度，似乎是评估牙齿冠状表面病变活动的最佳波长。
Previous studies have shown that large changes in the diffuse reflectivity of caries lesions during drying with air can be used to assess lesion activity. The largest changes occur at short wavelength infrared (SWIR) wavelengths coincident with high water absorption. The strongest water absorption in the SWIR occurs at 1950-nm. In this study changes in the reflectivity of simulated lesions with varying degrees of remineralization was measured at 1500–2340-nm and at 1950-nm as the samples were dried with air. Twenty bovine enamel surfaces each with 5 treatment windows were exposed to two demineralization/remineralization regimens to produce simulated lesions of varying depth, severity and mineral gradients. An extended range tungsten-halogen lamp with a long pass filter (1500–2340-nm) and a broadband ASE source centered near the peak of the water-absorption band at 1950-nm were used as light sources and an extended range InGaAs camera (1000–2340-nm) was used to acquire reflected light images as the samples were dried with air. Lesions were also assessed using digital microscopy, polarized light microscopy (PLM), optical coherence tomography (OCT), and transverse microradiography (TMR). Both wavelength ranges showed extremely high lesion contrast (> 0.9) for all six lesion treatment windows in both models. The change in contrast (ΔI) was significantly higher for the 1950-nm broadband source for all the intact lesion windows compared to the 1500–2340-nm wavelength range. SWIR light at 1950-nm yields extremely high contrast of demineralization and appears to be the optimum wavelength for the assessment of lesion activity on tooth coronal surfaces.
登录
查看更多内容
影响因子：
5
作者：
Kang, Hobin;Darling, Cynthia L.;Fried, Daniel
通讯作者：
Fried, Daniel
影响因子：
3.5
作者：
Ando, Masatoshi;Ferreira-Zandona, Andrea G.;Stookey, George K.
通讯作者：
Stookey, George K.
影响因子：
3.5
作者：
Chan, Kenneth H.;Fried, Daniel
通讯作者：
Fried, Daniel
影响因子：
3.5
作者：
Lee, Chulsung;Lee, Dustin;Fried, Daniel
通讯作者：
Fried, Daniel
影响因子：
3.4
作者：
Chung S;Fried D;Staninec M;Darling CL
通讯作者：
Darling CL