Determinants of body fat in infants of women with gestational diabetes mellitus differ with fetal sex.
Determinants of body fat in infants of women with gestational diabetes mellitus differ with fetal sex.
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DOI：
10.2337/dc11-0728
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发表时间：
2011-12
期刊：
影响因子：
16.2
通讯作者：
Callaway LK
中科院分区：
文献类型：
--
作者：
Lingwood BE;Henry AM;d'Emden MC;Fullerton AM;Mortimer RH;Colditz PB;Lê Cao KA;Callaway LK
新生儿肥胖是妊娠期糖尿病（GDM）的常见并发症。本研究旨在确定影响GDM孕妇产下的男婴和女婴肥胖的因素。这是一项对84名GDM妇女的前瞻性研究。从血糖仪中获取每日血糖水平（BGL），并计算每位女性的总体平均空腹和平均餐后2小时BGL。出生时测量婴儿身体成分，并进行回归分析，以确定显着的预测婴儿体脂肪分别在男性和女性婴儿。母亲空腹BGL是男婴肥胖的主要预测因子，但与女婴肥胖关系不大。在男婴中，母体平均空腹BGL每增加0.1 mmol/L，脂肪百分比增加0.44%。母亲BMI是女婴的主要预测因子，但对男婴影响不大。在女婴中，母亲孕前BMI每增加1 kg/m2，脂肪百分比增加0.11%。胎儿性别可能影响GDM治疗策略对婴儿肥胖的影响。
Neonatal adiposity is a well-recognized complication of gestational diabetes mellitus (GDM). This study aimed to identify factors influencing adiposity in male and female infants of women treated for GDM. This was a prospective study of 84 women with GDM. Daily blood glucose levels (BGLs) were retrieved from glucose meters, and overall mean fasting and mean 2-h postprandial BGLs were calculated for each woman. Infant body composition was measured at birth, and regression analysis was used to identify significant predictors of infant body fat separately in male and female infants. Maternal fasting BGL was the major predictor of adiposity in male infants but had little relationship to adiposity in female infants. In male infants, percent fat was increased by 0.44% for each 0.1 mmol/L increase in mean maternal fasting BGL. Maternal BMI was the primary predictor in female infants but had little effect in males. In female infants, percent fat was increased by 0.11% for each 1 kg/m2 increase in maternal prepregnancy BMI. Fetal sex may influence the impact that treatment strategies for GDM have on infant adiposity.
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影响因子：
16.2
作者：
Gillman MW;Oakey H;Baghurst PA;Volkmer RE;Robinson JS;Crowther CA
通讯作者：
Crowther CA
影响因子：
2.4
作者：
Pirc, Louise K;Owens, Julie A;Robinson, Jeffrey S
通讯作者：
Robinson, Jeffrey S
DOI：
10.1016/s0002-9378(03)00828-7
发表时间：
2003-12-01
影响因子：
9.8
作者：
Catalano, PM;Thomas, A;Amini, SB
通讯作者：
Amini, SB
影响因子：
9.8
作者：
Ehrenberg, HM;Mercer, BM;Catalano, PM
通讯作者：
Catalano, PM
糖尿病的医疗标准 - 2009年。
影响因子：
16.2
作者：
American Diabetes Association
通讯作者：
American Diabetes Association