UPDATES ON THE MECHANICS AND REGULATION OF CYTOKINESIS IN ANIMAL CELLS

UPDATES ON THE MECHANICS AND REGULATION OF CYTOKINESIS IN ANIMAL CELLS
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动物细胞细胞分裂机制和调控的最新进展

DOI:
--
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发表时间:
1999
影响因子:
3.9
通讯作者:
S. Wheatley
S. Wheatley
中科院分区:
生物学4区
文献类型:
--
作者:
S. Wheatley

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胞质分裂是有丝分裂后细胞分裂为两个子细胞的过程。为了确保只有一个基因组拷贝传递给每个子代,胞质分裂必须受到严格的调控,并与有丝分裂相协调。在动物细胞中,胞质分裂可以细分为许多阶段:卵裂平面选择;收缩器组装;沟进展;中间体形成;和子细胞分离(Glotzer,1997)。传统上,棘皮动物胚胎被用于研究胞质分裂,因为它们大而透明,这些特征便于显微操作和观察(Rappaport,1996)。然而,在成像技术的进步,有助于复兴的胞质分裂的研究与体细胞组织培养(TC)细胞的关注集中。因此,第一次直接检验了广泛持有的观点的普遍性。这些研究的结果导致研究人员重新评估细胞分裂的一些基本原则。我希望集中讨论这些最近的研究结果。更多的比较性综述见Field et al.(1999)。
Cytokinesis is the process by which a post-mitotic cell is cleaved into two daughter cells. To ensure that only one copy of the genome is transmitted to each daughter, cytokinesis must be tightly regulated and coordinated with mitosis. In animal cells, cytokinesis can be sub-divided into a number of stages: cleavage plane selection; contractile apparatus assembly; furrow progression; midbody formation; and daughter cell separation (Glotzer, 1997). Traditionally Echinoderm embryos have been used to study cytokinesis as they are large and transparent, characteristics which facilitate micromanipulation and observation (Rappaport, 1996). However, advances in imaging technology have contributed to a renaissance in the study of cytokinesis with much attention focussed on somatic tissue culture (TC) cells. Consequently the generality of the widely held views has been tested directly for the first time. The results of a number of these studies have led researchers to re-evaluate some of the basic tenets of cell division. It is on these recent findings that I wish to focus this review. For a more comparative review see Field et al. (1999).
胞质分裂期间与皮质细胞骨架相关的微管夹带激酶活性。
DOI: 10.1242/jcs.110.12.1373
发表时间: 1997
影响因子: 4
作者:
Walker,GR;Shuster,CB;Burgess,DR
通讯作者: Burgess,DR
DOI: --
发表时间: 1996-08
影响因子: 4
作者:
D. Fishkind;J. Silverman;Yu-li Wang
通讯作者: D. Fishkind;J. Silverman;Yu-li Wang
DOI: 10.1091/mbc.9.8.2037
发表时间: 1998-08-01
影响因子: 3.3
作者:
Raich, WB;Moran, AN;Hardin, J
通讯作者: Hardin, J
DOI: 10.1016/s1097-2765(00)80302-0
发表时间: 1998-12-01
期刊: MOLECULAR CELL
影响因子: 16
作者:
Jiang, W;Jimenez, G;Fukunaga, R
通讯作者: Fukunaga, R
DOI: 10.1091/mbc.7.2.225
发表时间: 1996-02-01
影响因子: 3.3
作者:
Cao, LG;Wang, YL
通讯作者: Wang, YL