Extracellular vesicle-derived miRNA as a novel regulatory system for bi-directional communication in gut-brain-microbiota axis.
Extracellular vesicle-derived miRNA as a novel regulatory system for bi-directional communication in gut-brain-microbiota axis.
复制标题
细胞外囊泡衍生的miRNA作为肠道 - 毛 - 微生物轴双向通信的新型调节系统。
DOI:
10.1186/s12967-021-02861-y
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发表时间:
2021-05-11
影响因子:
7.4
通讯作者:
Xiong X
中科院分区:
文献类型:
--
作者:
Zhao L;Ye Y;Gu L;Jian Z;Stary CM;Xiong X
The gut-brain-microbiota axis (GBMAx) coordinates bidirectional communication between the gut and brain, and is increasingly recognized as playing a central role in physiology and disease. MicroRNAs are important intracellular components secreted by extracellular vesicles (EVs), which act as vital mediators of intercellular and interspecies communication. This review will present current advances in EV-derived microRNAs and their potential functional link with GBMAx. We propose that EV-derived microRNAs comprise a novel regulatory system for GBMAx, and a potential novel therapeutic target for modifying GBMAx in clinical therapy.
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影响因子:
5.2
作者:
Cañas MA;Fábrega MJ;Giménez R;Badia J;Baldomà L
通讯作者:
Baldomà L
影响因子:
12.8
作者:
Chelakkot C;Choi Y;Kim DK;Park HT;Ghim J;Kwon Y;Jeon J;Kim MS;Jee YK;Gho YS;Park HS;Kim YK;Ryu SH
通讯作者:
Ryu SH
DOI:
10.1007/978-1-4939-0897-4_6
发表时间:
2014-01-01
期刊:
MICROBIAL ENDOCRINOLOGY: THE MICROBIOTA-GUT-BRAIN AXIS IN HEALTH AND DISEASE
影响因子:
--
作者:
Al Omran, Yasser;Aziz, Qasim
通讯作者:
Aziz, Qasim
影响因子:
11.1
作者:
Balusu S;Van Wonterghem E;De Rycke R;Raemdonck K;Stremersch S;Gevaert K;Brkic M;Demeestere D;Vanhooren V;Hendrix A;Libert C;Vandenbroucke RE
通讯作者:
Vandenbroucke RE
影响因子:
4.3
作者:
Cha, Diana J.;Mengel, David;Walsh, Dominic M.
通讯作者:
Walsh, Dominic M.