The effect of irrigation temperature on bone healing.

The effect of irrigation temperature on bone healing.
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DOI:
10.7150/ijms.8.704
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发表时间:
2011
影响因子:
3.6
通讯作者:
Cebi Z
Cebi Z
中科院分区:
医学4区
文献类型:
--
作者:
Isler SC;Cansiz E;Tanyel C;Soluk M;Selvi F;Cebi Z

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目的:旋转器械进行的截骨手术会引起骨温升高,温度升高会扰乱骨愈合。当为微型螺钉植入而进行截骨手术时,骨愈合中断可能会导致稳定性松动或失败。盐水冲洗主要用于预防截骨术中的发热。目的:探讨生理盐水冲洗温度对骨愈合的影响。材料和方法:对18只SD大鼠的胫骨进行标准化钻孔和微型螺丝钉置入,旋转钻未冷却,分别用25℃和4℃生理盐水灌流。21d后,观察未冷冻组与冷冻组愈合情况的差异。结果:25°C和4°C生理盐水灌洗组新生骨形成差异无统计学意义,但4°C组成骨细胞较25°C组活跃,骨髓活力较强。25°C组无不良影响,但以4°C组为佳。
Objective: Osteotomies, performed by rotational instruments, can cause temperature rise on the bone and elevated temperature can disrupt the bone healing. When the osteotomies are performed for the insertion of miniscrews, the bone healing disruption may cause stability loosening or failures. Saline irrigation is mostly used for the prevention of the heat generation during osteotomy. Purpose: The purpose of this study was to evaluate the effect of the saline irrigation temperature on bone healing. Material and Method: Standardized drilling and miniscrew placement was performed in the tibias of 18 Sprague Dawley rats with rotating bur uncooled, cooled with 25°C and 4°C saline irrigations. After the 21 days, the difference in healing was observed between the uncooled and cooled groups. Results: Although there was no statistically significant difference between the group irrigated with 25°C and 4°C saline for newly bone formation, osteoblasts were seen more active and bone marrow was more dynamic in group 4°C than group 25°C. There is no disadvantage to use 25°C, but it may be better to use 4°C for rapid healing.
DOI: 10.1053/j.jfas.2009.03.009
发表时间: 2009-07-01
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