Nuclear jasmonate and salicylate signaling and crosstalk in defense against pathogens.
Nuclear jasmonate and salicylate signaling and crosstalk in defense against pathogens.
复制标题
DOI：
10.3389/fpls.2013.00072
复制
发表时间：
2013
影响因子：
5.6
通讯作者：
Solano R
中科院分区：
文献类型：
--
作者：
Gimenez-Ibanez S;Solano R
过去二十年来，在了解植物先天免疫的组成部分和机制方面取得了非凡的进展。在检测到病原体后，植物的有效抗性取决于小信号分子和激素途径整合的复杂信号网络的激活，而这些激素系统的平衡决定了对特定病原体的抗性。激素信号通路新成分（包括植物核激素受体）的发现，提供了一幅复杂串扰和诱导激素变化的图景，这些变化通过几个蛋白质家族调节疾病和抵抗力，这些蛋白质家族感知细胞核内的激素，并导致通常通过去抑制实现的大规模基因诱导反应。这篇综述强调了我们对这些激素信号通路的正负调节因子的理解的最新进展，这些激素信号传导途径是疾病和防御中激素串扰的关键调节目标。我们重点关注茉莉酸和水杨酸途径成分的最新发现，这些成分解释了它们与细胞核中其他激素途径的串扰。我们讨论了这些成分如何微调防御反应，以建立针对大量不同微生物的强大植物免疫系统，最后，我们总结了微生物对特定核激素操纵的最新发现，这些发现举例说明了病原体可以控制植物激素信号网络以促进疾病的巧妙方式。
An extraordinary progress has been made over the last two decades on understanding the components and mechanisms governing plant innate immunity. After detection of a pathogen, effective plant resistance depends on the activation of a complex signaling network integrated by small signaling molecules and hormonal pathways, and the balance of these hormone systems determines resistance to particular pathogens. The discovery of new components of hormonal signaling pathways, including plant nuclear hormone receptors, is providing a picture of complex crosstalk and induced hormonal changes that modulate disease and resistance through several protein families that perceive hormones within the nucleus and lead to massive gene induction responses often achieved by de-repression. This review highlights recent advances in our understanding of positive and negative regulators of these hormones signaling pathways that are crucial regulatory targets of hormonal crosstalk in disease and defense. We focus on the most recent discoveries on the jasmonate and salicylate pathway components that explain their crosstalk with other hormonal pathways in the nucleus. We discuss how these components fine-tune defense responses to build a robust plant immune system against a great number of different microbes and, finally, we summarize recent discoveries on specific nuclear hormonal manipulation by microbes which exemplify the ingenious ways by which pathogens can take control over the plant’s hormone signaling network to promote disease.
登录
查看更多内容
DOI：
10.1073/pnas.0704901104
发表时间：
2007-12-11
影响因子：
11.1
作者：
Chen, Zhongying;Agnew, Jennifer L.;Kunkel, Barbara N.
通讯作者：
Kunkel, Barbara N.
影响因子：
11.8
作者：
Choi, Jaemyung;Huh, Sung Un;Hwang, Ildoo
通讯作者：
Hwang, Ildoo
影响因子：
2.9
作者：
Canonne, Joanne;Rivas, Susana
通讯作者：
Rivas, Susana
影响因子：
56.9
作者：
BLEECKER, AB;ESTELLE, MA;KENDE, H
通讯作者：
KENDE, H
影响因子：
56.9
作者：
Boch, Jens;Scholze, Heidi;Bonas, Ulla
通讯作者：
Bonas, Ulla