Alterations in regional homogeneity of resting-state brain activity in internet gaming addicts.
Alterations in regional homogeneity of resting-state brain activity in internet gaming addicts.
复制标题
网络游戏成瘾者静息态大脑活动区域同质性的变化
DOI：
10.1186/1744-9081-8-41
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发表时间：
2012-08-18
期刊：
影响因子：
--
通讯作者：
Du X
中科院分区：
文献类型：
--
作者：
Dong G;Huang J;Du X
研究背景网络游戏成瘾（伊加）作为网络成瘾的一种亚型，正迅速成为世界范围内普遍关注的心理健康问题。应研究伊加的神经生物学基础，以揭示伊加的潜在异质性。本研究采用静息态fMRI技术对伊加患者的脑功能进行了研究。区域同质性（ReHo）的措施被用来检测异常的功能integrations.ResultsComparing健康controls.伊加科目显示增强ReHo在脑干，顶下小叶，左后小脑，左额中回。所有这些区域都被认为与感觉运动协调有关。此外，伊加受试者在颞叶、枕叶和顶叶脑区显示ReHo降低。这些区域被认为是负责视觉和听觉functions.ConclusionsOur结果表明，长时间的在线游戏玩增强了大脑同步的感觉-运动协调相关的脑区，降低了视觉和听觉相关的脑区的兴奋性。
BackgroundsInternet gaming addiction (IGA), as a subtype of internet addiction disorder, is rapidly becoming a prevalent mental health concern around the world. The neurobiological underpinnings of IGA should be studied to unravel the potential heterogeneity of IGA. This study investigated the brain functions in IGA patients with resting-state fMRI.MethodsFifteen IGA subjects and fourteen healthy controls participated in this study. Regional homogeneity (ReHo) measures were used to detect the abnormal functional integrations.ResultsComparing to the healthy controls, IGA subjects show enhanced ReHo in brainstem, inferior parietal lobule, left posterior cerebellum, and left middle frontal gyrus. All of these regions are thought related with sensory-motor coordination. In addition, IGA subjects show decreased ReHo in temporal, occipital and parietal brain regions. These regions are thought responsible for visual and auditory functions.ConclusionsOur results suggest that long-time online game playing enhanced the brain synchronization in sensory-motor coordination related brain regions and decreased the excitability in visual and auditory related brain regions.
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影响因子：
2.6
作者：
Kojima, Haruyuki;Suzuki, Takeshi
通讯作者：
Suzuki, Takeshi
影响因子：
14.5
作者：
Kalenine, Solene;Buxbaum, Laurel J.;Coslett, Harry Branch
通讯作者：
Coslett, Harry Branch
DOI：
10.3109/00952990.2010.491884
发表时间：
2010-09
期刊：
The American journal of drug and alcohol abuse
影响因子：
--
作者：
Grant JE;Potenza MN;Weinstein A;Gorelick DA
通讯作者：
Gorelick DA
影响因子：
3.7
作者：
DellaCroce, John T.;Vitale, Albert T.
通讯作者：
Vitale, Albert T.
前兆或后遗症：网络成瘾者的病理障碍
影响因子：
3.7
作者：
Dong G;Lu Q;Zhou H;Zhao X
通讯作者：
Zhao X