Coronavirus replication and pathogenesis: Implications for the recent outbreak of severe acute respiratory syndrome (SARS), and the challenge for vaccine development.

Coronavirus replication and pathogenesis: Implications for the recent outbreak of severe acute respiratory syndrome (SARS), and the challenge for vaccine development.
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DOI:
10.1080/13550280490280292
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发表时间:
2004-04
影响因子:
3.2
通讯作者:
Weiss S
Weiss S
中科院分区:
医学4区
文献类型:
--
作者:
Navas-Martín SR;Weiss S

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一种新型冠状病毒最近被确定为严重急性呼吸系统综合症(SARS)爆发的病原体,该疾病已在全球造成8000多人感染。本文将讨论目前关于冠状病毒复制、发病机制、进化和疫苗策略的知识,以及关于SARS冠状病毒的最新发现。
A novel coronavirus has been recently identified as the causative agent of the severe acute respiratory syndrome (SARS) outbreak that has accounted for more than 8000 infected people worldwide. This review will discuss current knowledge on coronavirus replication, pathogenesis, evolution, and vaccine strategies, as well as the most recent findings on SARS coronavirus.
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