Manipulation of the Geometry and Modulation of the Optical Response of Surfactant-Free Gold Nanostars: A Systematic Bottom-Up Synthesis.
Manipulation of the Geometry and Modulation of the Optical Response of Surfactant-Free Gold Nanostars: A Systematic Bottom-Up Synthesis.
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DOI：
10.1021/acsomega.7b01700
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发表时间：
2018-02-28
期刊：
影响因子：
4.1
通讯作者：
Vo-Dinh T
中科院分区：
文献类型：
--
作者：
De Silva Indrasekara AS;Johnson SF;Odion RA;Vo-Dinh T
在等离子体纳米颗粒中，不含表面活性剂的支化金纳米颗粒作为纳米平台表现出卓越的性能，可用于各种应用，从表面增强拉曼散射传感和成像应用到癌症治疗的光热治疗和光免疫治疗。支化金纳米粒子在生物医学应用中的有效性和可靠性强烈依赖于纳米粒子的物理、化学、光学和治疗性质的一致性和再现性，这主要取决于其形态特征。在此，我们提出了一种优化的自下而上的合成，提高了具有所需形态特征和光学性质的金支化纳米颗粒的再现性和均匀性。我们发现，试剂添加的顺序对于改善纳米颗粒的支化性质的均匀性至关重要，这使得批次间的重现性和可靠性高。此外，实现了合成参数的不同组合，特别是添加剂卤化物和反应性Au与Ag和Au与Au种子的浓度比，其产生具有类似局部表面等离子体共振但具有分支尺寸的可区分变化的分支纳米颗粒。总的来说，我们的研究介绍了以可靠的方式定制制造无表面活性剂的金纳米星的设计参数。
Among plasmonic nanoparticles, surfactant-free branched gold nanoparticles have exhibited exceptional properties as a nanoplatform for a wide variety of applications ranging from surface-enhanced Raman scattering sensing and imaging applications to photothermal treatment and photoimmunotherapy for cancer treatments. The effectiveness and reliability of branched gold nanoparticles in biomedical applications strongly rely on the consistency and reproducibility of physical, chemical, optical, and therapeutic properties of nanoparticles, which are mainly governed by their morphological features. Herein, we present an optimized bottom-up synthesis that improves the reproducibility and homogeneity of the gold-branched nanoparticles with desired morphological features and optical properties. We identified that the order of reagent addition is crucial for improved homogeneity of the branched nature of nanoparticles that enable a high batch-to-batch reproducibility and reliability. In addition, a different combination of the synthesis parameters, in particular, additive halides and concentration ratios of reactive Au to Ag and Au to Au seeds, which yield branched nanoparticle of similar localized surface plasmon resonances but with distinguishable changes in the dimensions of the branches, was realized. Overall, our study introduces the design parameters for the purpose-tailored manufacturing of surfactant-free gold nanostars in a reliable manner.
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影响因子：
3.7
作者：
de Puig, Helena;Tam, Justina O.;Yen, Chun-Wan;Gehrke, Lee;Hamad-Schifferli, Kimberly
通讯作者：
Hamad-Schifferli, Kimberly
影响因子：
10.8
作者：
Hao, Feng;Nehl, Colleen L.;Nordlander, Peter
通讯作者：
Nordlander, Peter
影响因子：
3.7
作者：
Hoener, Benjamin S.;Byers, Chad P.;Landes, Christy F.
通讯作者：
Landes, Christy F.
影响因子：
7.4
作者：
Hendel, Thomas;Wuithschick, Maria;Polte, Joerg
通讯作者：
Polte, Joerg
DOI：
10.1021/la202602q
发表时间：
2011-10-04
期刊：
Langmuir : the ACS journal of surfaces and colloids
影响因子：
--
作者：
Fales AM;Yuan H;Vo-Dinh T
通讯作者：
Vo-Dinh T