Sensors for detecting pulmonary diseases from exhaled breath.

Sensors for detecting pulmonary diseases from exhaled breath.
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DOI:
10.1183/16000617.0011-2019
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发表时间:
2019-06-30
期刊:
European respiratory review : an official journal of the European Respiratory Society
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其他
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这篇综述介绍并讨论了一个新的前沿快速,无风险和潜在的廉价诊断呼吸系统疾病的检测挥发性有机化合物(VOCs)存在于呼出气。其中一部分的审查是一个教学介绍的叠加概念和化学呼出气。另一部分讨论了各种传感器,这些传感器已被开发并用于通过分析呼出气体中的VOC来检测呼吸系统疾病(例如慢性阻塞性肺病、哮喘、肺癌、肺动脉高压、肺结核、囊性纤维化、阻塞性睡眠呼吸暂停综合征和尘肺病)。的优势和陷阱进行了讨论和批评,特别是在传播有关这些进步的信息的角度。文中还讨论了传感器、传感器阵列、传感装置的改进以及工作流程的进一步规划。通过基于纳米材料的传感器检测呼出气体中的挥发性有机化合物是肺部疾病筛查中的新诊断前沿。http://bit.ly/2JoBKXn
This review presents and discusses a new frontier for fast, risk-free and potentially inexpensive diagnostics of respiratory diseases by detecting volatile organic compounds (VOCs) present in exhaled breath. One part of the review is a didactic presentation of the overlaying concept and the chemistry of exhaled breath. The other part discusses diverse sensors that have been developed and used for the detection of respiratory diseases (e.g. chronic obstructive pulmonary disease, asthma, lung cancer, pulmonary arterial hypertension, tuberculosis, cystic fibrosis, obstructive sleep apnoea syndrome and pneumoconiosis) by analysis of VOCs in exhaled breath. The strengths and pitfalls are discussed and criticised, particularly in the perspective in disseminating information regarding these advances. Ideas regarding the improvement of sensors, sensor arrays, sensing devices and the further planning of workflow are also discussed. Detection of volatile organic compounds from exhaled breath by nanomaterial-based sensors is a new diagnostics frontier in the screening of pulmonary diseases. http://bit.ly/2JoBKXn
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