Ecological niche and geographic distribution of human monkeypox in Africa.
Ecological niche and geographic distribution of human monkeypox in Africa.
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DOI：
10.1371/journal.pone.0000176
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发表时间：
2007-01-31
期刊：
影响因子：
3.7
通讯作者：
Reynolds MG
中科院分区：
文献类型：
--
作者：
Levine RS;Peterson AT;Yorita KL;Carroll D;Damon IK;Reynolds MG
猴痘病毒是正痘病毒科的一种人畜共患病毒，可引起人类严重的天花样疾病。猴痘病毒被认为是西非和中非森林地区的地方病。关于人类猴痘病的发生比关于该病毒在非人类动物宿主中的自然森林化循环知道得多。我们使用1970-2003年非洲人猴痘病例数据，在生态位建模框架中构建猴痘病毒在西非和中非的生态需求和地理分布的预测模型。使用不同的输入数据子集的内部预测能力的测试表明，该模型是非常强大的，并建议在西非和中非的猴痘不同的系统发育谱系占据类似的生态位。高的年平均降水量和低海拔被证明与人类猴痘病的发生高度相关。本研究得出的非洲人猴痘潜在地理分布的综合图应支持正在进行的流行病学和生态学研究，并有助于指导对人猴痘风险最高地区的公共卫生干预策略。
Monkeypox virus, a zoonotic member of the genus Orthopoxviridae, can cause a severe, smallpox-like illness in humans. Monkeypox virus is thought to be endemic to forested areas of western and Central Africa. Considerably more is known about human monkeypox disease occurrence than about natural sylvatic cycles of this virus in non-human animal hosts. We use human monkeypox case data from Africa for 1970–2003 in an ecological niche modeling framework to construct predictive models of the ecological requirements and geographic distribution of monkeypox virus across West and Central Africa. Tests of internal predictive ability using different subsets of input data show the model to be highly robust and suggest that the distinct phylogenetic lineages of monkeypox in West Africa and Central Africa occupy similar ecological niches. High mean annual precipitation and low elevations were shown to be highly correlated with human monkeypox disease occurrence. The synthetic picture of the potential geographic distribution of human monkeypox in Africa resulting from this study should support ongoing epidemiologic and ecological studies, as well as help to guide public health intervention strategies to areas at highest risk for human monkeypox.
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影响因子：
11.8
作者：
Peterson AT;Sánchez-Cordero V;Beard CB;Ramsey JM
通讯作者：
Ramsey JM
DOI：
10.4269/ajtmh.1985.34.781
发表时间：
1985-01-01
影响因子：
3.3
作者：
ARITA, I;JEZEK, Z;RUTI, K
通讯作者：
RUTI, K
影响因子：
3.1
作者：
Stockwell, DRB;Peterson, AT
通讯作者：
Peterson, AT
DOI：
10.1080/136588199241391
发表时间：
1999-03-01
影响因子：
5.7
作者：
Stockwell, D;Peters, D
通讯作者：
Peters, D
影响因子：
4
作者：
Peterson, AT;Shaw, J
通讯作者：
Shaw, J