Post-reductionist protein science, or putting Humpty Dumpty back together again.
Post-reductionist protein science, or putting Humpty Dumpty back together again.
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DOI：
10.1038/nchembio.241
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发表时间：
2009-11
影响因子：
14.8
通讯作者：
Gershenson, Anne
中科院分区：
文献类型：
--
作者：
Gierasch, Lila M.;Gershenson, Anne
In their native environments, proteins perform their biological roles in highly concentrated viscous solutions and in complex networks with numerous partners. Yet for many years, the normal practice has been to purify a protein of interest in order to characterize its structural and functional properties. In this Commentary, we discuss how protein scientists are now tackling the theoretical and methodological challenges of studying proteins in their physiological context.
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DOI：
10.1126/science.1162609
发表时间：
2008-10-17
期刊：
Science (New York, N.Y.)
影响因子：
--
作者：
Roguev A;Bandyopadhyay S;Zofall M;Zhang K;Fischer T;Collins SR;Qu H;Shales M;Park HO;Hayles J;Hoe KL;Kim DU;Ideker T;Grewal SI;Weissman JS;Krogan NJ
通讯作者：
Krogan NJ
影响因子：
7.5
作者：
Hoenger A;McIntosh JR
通讯作者：
McIntosh JR
影响因子：
--
作者：
Kempner, ES;Miller, JH
通讯作者：
Miller, JH
影响因子：
6.8
作者：
Stein, Matthias;Gabdoulline, Razif R.;Wade, Rebecca C.
通讯作者：
Wade, Rebecca C.
体内羟基自由基足迹：用同步辐射绘制大分子结构。
影响因子：
14.9
作者：
Adilakshmi, Tadepalli;Lease, Richard A.;Woodson, Sarah A.
通讯作者：
Woodson, Sarah A.