Plant nucleolar DNA: Green light shed on the role of Nucleolin in genome organization
Plant nucleolar DNA: Green light shed on the role of Nucleolin in genome organization
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植物核仁 DNA:核仁蛋白在基因组组织中的作用亮了绿灯
DOI:
10.1080/19491034.2016.1236167
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发表时间:
2017
期刊:
影响因子:
3.7
通讯作者:
Frédéric Pontvianne
中科院分区:
文献类型:
--
作者:
Claire Picart;Frédéric Pontvianne
ABSTRACT The nucleolus forms as a consequence of ribosome biogenesis, but it is also implicated in other cell functions. The identification of nucleolus-associated chromatin domains (NADs) in animal and plant cells revealed the presence of DNA sequences other than rRNA genes in and around the nucleolus. NADs display repressive chromatin signatures and harbour repetitive DNA, but also tRNA genes and RNA polymerase II-transcribed genes. Furthermore, the identification of NADs revealed a specific function of the nucleolus and the protein Nucleolin 1 (NUC1) in telomere biology. Here, we discuss the significance of these data with regard to nucleolar structure and to the role of the nucleolus and NUC1 in global genome organization and stability.
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影响因子:
16
作者:
Padeken, Jan;Mendiburo, Maria Jose;Heun, Patrick
通讯作者:
Heun, Patrick
影响因子:
8.8
作者:
Pontvianne F;Carpentier MC;Durut N;Pavlištová V;Jaške K;Schořová Š;Parrinello H;Rohmer M;Pikaard CS;Fojtová M;Fajkus J;Sáez-Vásquez J
通讯作者:
Sáez-Vásquez J
影响因子:
10.5
作者:
Pontvianne, Frederic;Blevins, Todd;Pikaard, Craig S.
通讯作者:
Pikaard, Craig S.
影响因子:
10.5
作者:
Earley, Keith W.;Pontvianne, Frederic;Pikaard, Craig S.
通讯作者:
Pikaard, Craig S.