The Diagnosis and Management of Cardiometabolic Risk and Cardiometabolic Syndrome after Spinal Cord Injury.

The Diagnosis and Management of Cardiometabolic Risk and Cardiometabolic Syndrome after Spinal Cord Injury.
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DOI:
10.3390/jpm12071088
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发表时间:
2022-06-30
影响因子:
--
通讯作者:
Gater, David R. Jr Jr
Gater, David R. Jr Jr
中科院分区:
医学4区
文献类型:
--
作者:
Farkas, Gary J.;Burton, Adam M.;McMillan, David W.;Sneij, Alicia;Gater, David R. Jr Jr

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脊髓损伤(SCI)患者通常存在心脏代谢风险的组成风险因素和心脏代谢综合征(CMS)的综合风险因素。这些主要风险因素包括肥胖、血脂异常、代谢紊乱/胰岛素抵抗和高血压。通常被称为“沉默的杀手”,心脏代谢风险和CMS增加了心血管疾病的威胁,这是SCI后死亡的主要原因。这篇叙述性综述将检查当前的数据和心脏代谢风险、CMS和与SCI相关的心血管疾病的发病机制,重点关注过去五年来关于心脏代谢后遗症的关键研究。该综述还将提供SCI后心脏代谢紊乱的当前诊断和监测标准,一种基于总体脂百分比的新型肥胖分类系统,以及改善心脏代谢健康的生活方式管理策略。
Individuals with spinal cord injuries (SCI) commonly present with component risk factors for cardiometabolic risk and combined risk factors for cardiometabolic syndrome (CMS). These primary risk factors include obesity, dyslipidemia, dysglycemia/insulin resistance, and hypertension. Commonly referred to as “silent killers”, cardiometabolic risk and CMS increase the threat of cardiovascular disease, a leading cause of death after SCI. This narrative review will examine current data and the etiopathogenesis of cardiometabolic risk, CMS, and cardiovascular disease associated with SCI, focusing on pivotal research on cardiometabolic sequelae from the last five years. The review will also provide current diagnosis and surveillance criteria for cardiometabolic disorders after SCI, a novel obesity classification system based on percent total body fat, and lifestyle management strategies to improve cardiometabolic health.
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