Four-Analog Computation Based on DNA Strand Displacement.

Four-Analog Computation Based on DNA Strand Displacement.
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基于DNA链位移的四模拟计算

DOI:
10.1021/acsomega.7b00572
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发表时间:
2017-08-31
期刊:
影响因子:
4.1
通讯作者:
Liu Y
Liu Y
中科院分区:
化学3区
文献类型:
--
作者:
Zou C;Wei X;Zhang Q;Liu C;Zhou C;Liu Y

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DNA链置换在生物计算中起着重要的作用。并行性、高可存储性和级联的固有优点导致了在纳米尺度上增加DNA链置换的功能电路实现。在此,我们提出了一种基于DNA链置换的减法模拟计算。加、减、乘、除门作为基本门,可以实现带负号的模拟运算。该方案的优点是模拟计算的负值和除法计算。在这篇文章中,我们提供了这些基本门的设计和原理,并通过模拟演示门的性能。此外,为了说明门的级联特性,我们还计算了一个多项式作为例子。
DNA strand displacement plays an important role in biological computations. The inherent advantages of parallelism, high storability, and cascading have resulted in increased functional circuit realization of DNA strand displacement on the nanoscale. Herein, we propose an analog computation with minus based on DNA strand displacement. The addition, subtraction, multiplication, and division gates as elementary gates could realize analog computation with minus. The advantages of this proposal are the analog computation with negative value and division computation. In this article, we provide the designs and principles of these elementary gates and demonstrate gate performance by simulation. Furthermore, to show the cascade property of gates, we computed a polynomial as an example by these gates.
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