Detection of breast cancer microcalcifications using a dual-modality SPECT/NIR fluorescent probe.

Detection of breast cancer microcalcifications using a dual-modality SPECT/NIR fluorescent probe.
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DOI:
10.1021/ja807099s
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发表时间:
2008-12-31
影响因子:
15
通讯作者:
Frangioni JV
Frangioni JV
中科院分区:
化学1区
文献类型:
--
作者:
Bhushan KR;Misra P;Liu F;Mathur S;Lenkinski RE;Frangioni JV

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Efficient chemical synthesis of a trifunctional, hydroxyapatite-binding molecule, which provides simultaneousin vivoimaging by NIR fluorescence and SPECT/CT has been described. Quantitation by SPECT provides the “gold standard” by which NIR fluorescence tomography of breast cancer microcalcifications can now be compared and optimized.
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