Painted radioluminescence imaging with radioluminescent nanophosphors
Painted radioluminescence imaging with radioluminescent nanophosphors
复制标题
使用放射发光纳米磷光体绘制放射发光成像
DOI:
10.1063/5.0130428
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发表时间:
2022-12
影响因子:
4
通讯作者:
Cao Xu
中科院分区:
文献类型:
--
作者:
Bai Tingting;Kang Fei;Zhu Shouping;Chen Xueli;Wang Yihan;Cao Xu
Optical strategies like Cerenkov luminescence imaging (CLI) or radioluminescence imaging (RLI) to image clinically available positron emission tomography and single photon emission computed tomography probes still suffer from low sensitivity or resolution. This study investigated a painted radioluminescence imaging (PRLI) approach that employed a painted scintillator to improve signal and resolution for imaging clinical used 18F-fluorinated deoxyribose (18F-FDG). Results of phantom and in vivo experiments revealed that PRLI could achieve ∼100 times higher signal intensity than CLI and higher resolution compared to Flexible radioluminescence imaging (FRLI), a flexible scintillation-based RLI. PRLI increased signal-to-background ratio in the pseudotumor model by 81.8% (compared to CLI) and 73.9% (compared to FRLI) as well as in the tumor model by 60.0% (compared to CLI) and 33.3% (compared to FRLI). As a conclusion, PRLI is a more effective optical approach for detecting tumors using 18F-FDG.
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影响因子:
9.5
作者:
Cao, Xin;Chen, Xueli;Tian, Jie
通讯作者:
Tian, Jie
影响因子:
3.7
作者:
Liu H;Ren G;Miao Z;Zhang X;Tang X;Han P;Gambhir SS;Cheng Z
通讯作者:
Cheng Z
DOI:
10.1088/0508-3443/6/7/301
发表时间:
1955-01-01
期刊:
BRITISH JOURNAL OF APPLIED PHYSICS
影响因子:
--
作者:
JELLEY, JV
通讯作者:
JELLEY, JV
影响因子:
9.3
作者:
King, Martin T.;Carpenter, Colin M.;Xing, Lei
通讯作者:
Xing, Lei
影响因子:
29.4
作者:
Sun, Conroy;Pratx, Guillem;Carpenter, Colin M.;Liu, Hongguang;Cheng, Zhen;Gambhir, Sanjiv Sam;Xing, Lei
通讯作者:
Xing, Lei