Effects of cardiorespiratory fitness on aging: glucose trajectory in a cohort of healthy men.
Effects of cardiorespiratory fitness on aging: glucose trajectory in a cohort of healthy men.
复制标题
DOI：
10.1016/j.annepidem.2012.05.005
复制
发表时间：
2012-09
影响因子：
5.6
通讯作者：
Blair, Steven N.
中科院分区：
文献类型：
--
作者：
Sui, Xuemei;Jackson, Andrew S.;Church, Timothy S.;Lee, Duck-Chul;O'Connor, Daniel P.;Liu, Jihong;Blair, Steven N.
We modeled the age-related trajectory of glucose and determined if cardiorespiratory fitness altered the trajectory in a cohort of men from the Aerobics Center Longitudinal Study. 10,092 men free of diagnosed diabetes, CVD, and cancer, aged 20 to 90 years, completed from 2 to 21 health examinations between 1977 and 2005. Cardiorespiratory fitness was measured by a maximal treadmill exercise test and normalized for age. The covariates included waist circumference, hypertension, elevated cholesterol, smoking behavior and physical activity. Linear mixed models regression analysis showed that fasting glucose increased at a linear rate with aging. Glucose increased at a yearly rate of 0.17 mg/dL (95% confidence interval: 0.16, 0.19). Fitness had little influence on the aging glucose trajectory below age 35, but significantly influenced the trend after age 35 (P for interaction <0.001). The aging-related glucose increases in low fit men (0.25 mg/dL per year) was higher than average fit (0.15 mg/dL per year) and high fit (0.13 mg/dL per year) men. The aging-related glucose increases in low fit men was nearly double that of high fit men. Our results may suggest that it is possible to delay the age-related glucose impairment through increasing one’s fitness.
登录
查看更多内容
影响因子：
16.2
作者：
Lee DC;Sui X;Church TS;Lee IM;Blair SN
通讯作者：
Blair SN
影响因子：
5
作者：
KOHL, HW;BLAIR, SN;KRONENFELD, JJ
通讯作者：
KRONENFELD, JJ
DOI：
10.1097/00005768-199901000-00004
发表时间：
1999-01-01
期刊：
MEDICINE AND SCIENCE IN SPORTS AND EXERCISE
影响因子：
--
作者：
Evans, WJ
通讯作者：
Evans, WJ
影响因子：
2.8
作者：
Gibbons, LW;Mitchell, TL;Cooper, KH
通讯作者：
Cooper, KH
影响因子：
3.6
作者：
Jackson, Andrew S.;Janssen, Ian;Blair, Steven N.
通讯作者：
Blair, Steven N.