HPLC analysis of eluted monomers from two composite resins cured with LED and halogen curing lights.
HPLC analysis of eluted monomers from two composite resins cured with LED and halogen curing lights.
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对两种用 LED 和卤素固化灯固化的复合树脂中洗脱的单体进行 HPLC 分析。
DOI：
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发表时间：
2009
期刊：
影响因子：
--
通讯作者：
M. Kharrazi
中科院分区：
文献类型：
--
作者：
M. Tabatabaee;Hosein Mahdavi;S. Zandi;M. Kharrazi
本研究研究了用LED或传统卤素固化灯固化纳米混合（Filtek Supreme）和流动（Filtek Flow）牙科复合树脂中单体（Bis-GMA和TEGDMA）的浸出，并将其浸泡在唾液或水中24小时。每个实验组制作9个光盘标本。聚合过程结束后，将样品浸入水或唾液中，37℃孵育24 h。洗脱后的Bis-GMA和TEGDMA单体采用高效液相色谱（HPLC）检测。数据分析采用三向方差分析（p = 0.05）和独立样本t检验。无论复合材料类型、溶剂（介质）和固化光类型如何，TEGDMA （53.15-1 μ g/L）的浸出量均高于Bis-GMA (28-0.5 μ g/L) （p < 0.01）。总的来说，Filtek Flow树脂比Filtek Supreme树脂释放更多的TEGDMA (p < 0.05)，而Supreme树脂释放更多的Bis-GMA比TEGDMA （p < 0.05）。卤素光诱导的单体洗脱比LED光浸泡在水中更大。唾液中TEGDMA的释放量高于水（p < 0.05）。结果表明：(1)总浸出TEGDMA高于总Bis-GMA，(2)唾液和卤素光（强度低于LED）从树脂中浸出更多的单体，(3)可流动复合树脂比纳米复合树脂浸出更多的TEGDMA。
This study investigated the leaching of monomers (Bis-GMA and TEGDMA) from nano-hybrid (Filtek Supreme) and flowable (Filtek Flow) dental composite resins cured with LED or conventional halogen curing lights, and immersed in saliva or water for 24 h. Nine disc specimens were made for each experimental group. After the polymerization process, the specimens were immersed in either water or saliva and incubated at 37 degrees C for 24 h. Eluted Bis-GMA and TEGDMA monomers were detected using high performance liquid chromatography (HPLC). The data were analyzed using three-way ANOVA (p = 0.05) and the independent samples t test. TEGDMA (53.15-1 microg/L) was leached from the resins at a higher level than Bis-GMA (28-0.5 microg/L) (p < 0.01), regardless of the affecting factors: composite type, solvent (media) and type of curing light. In general, Filtek Flow resin released more TEGDMA than Filtek Supreme (p < 0.05), but the Supreme resin released more Bis-GMA than TEGDMA (p < 0.05). Halogen light induced greater monomer elution than LED light immersion in water. Saliva released more TEGDMA than water (p < 0.05). We conclude that (1) total leached TEGDMA was higher than total Bis-GMA, (2) saliva and halogen light (lower intensity than LED) leached more monomers from the resins, and (3) the flowable composite resin leached more TEGDMA than the nano-hybrid.
BIS-GMA 牙科复合材料在有机溶剂中浸出前后的细胞毒性。
DOI：
10.1002/jbm.820250403
发表时间：
1991
期刊：
Journal of biomedical materials research
影响因子：
--
作者：
Rathbun,MA;Craig,RG;Hanks,CT;Filisko,FE
通讯作者：
Filisko,FE
影响因子：
5
作者：
Hanks, CT;Wataha, JC;Sun, ZL
通讯作者：
Sun, ZL
影响因子：
2.9
作者：
FERRACANE, JL
通讯作者：
FERRACANE, JL