Age groups that sustain resurging COVID-19 epidemics in the United States.
Age groups that sustain resurging COVID-19 epidemics in the United States.
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DOI：
10.1126/science.abe8372
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发表时间：
2021-03-26
期刊：
影响因子：
--
通讯作者：
Imperial College COVID-19 Response Team
中科院分区：
文献类型：
--
作者：
Monod M;Blenkinsop A;Xi X;Hebert D;Bershan S;Tietze S;Baguelin M;Bradley VC;Chen Y;Coupland H;Filippi S;Ish-Horowicz J;McManus M;Mellan T;Gandy A;Hutchinson M;Unwin HJT;van Elsland SL;Vollmer MAC;Weber S;Zhu H;Bezancon A;Ferguson NM;Mishra S;Flaxman S;Bhatt S;Ratmann O;Imperial College COVID-19 Response Team
在最初的下降之后，2020年中期，美国和欧洲出现了新型冠状病毒病（COVID-19）传播的复苏。随着covid - 19疾病控制工作的重新加强，了解推动传播的年龄人口特征以及这些特征如何影响干预措施的放松至关重要。我们分析了来自美国1000多万人的特定年龄的总体流动性趋势，并将这些趋势与特定年龄的COVID-19死亡率数据机械地联系起来。我们估计，截至2020年10月，20-49岁的个体是唯一一个再生数远高于1的SARS-CoV-2传播复苏的年龄组，并且100例COVID-19感染中至少有65例来自美国20-49岁的个体。针对20-49岁的成年人采取干预措施（包括传播阻断疫苗），是遏制疫情死灰复燃和预防covid -19导致死亡的一个重要考虑因素。
Following initial declines, in mid 2020 a resurgence in transmission of novel coronavirus disease (COVID-19) occurred in the US and Europe. As COVID19 disease control efforts are re-intensified, understanding the age demographics driving transmission and how these affect the loosening of interventions is crucial. We analyze aggregated, age-specific mobility trends from more than 10 million individuals in the US and link these mechanistically to age-specific COVID-19 mortality data. We estimate that as of October 2020, individuals aged 20-49 are the only age groups sustaining resurgent SARS-CoV-2 transmission with reproduction numbers well above one, and that at least 65 of 100 COVID-19 infections originate from individuals aged 20-49 in the US. Targeting interventions – including transmission-blocking vaccines – to adults aged 20-49 is an important consideration in halting resurgent epidemics and preventing COVID-19-attributable deaths.
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影响因子：
64.8
作者：
Crackower, MA;Sarao, R;Penninger, JM
通讯作者：
Penninger, JM
影响因子：
5.8
作者：
Carpenter, Bob;Gelman, Andrew;Riddell, Allen
通讯作者：
Riddell, Allen
影响因子：
3.8
作者：
Aiello AE;Simanek AM;Eisenberg MC;Walsh AR;Davis B;Volz E;Cheng C;Rainey JJ;Uzicanin A;Gao H;Osgood N;Knowles D;Stanley K;Tarter K;Monto AS
通讯作者：
Monto AS
DOI：
10.1098/rstb.2004.1490
发表时间：
2004-07-29
影响因子：
6.3
作者：
Anderson, RM;Fraser, C;Hedley, AJ
通讯作者：
Hedley, AJ
DOI：
10.15585/mmwr.mm6939e1
发表时间：
2020-10-02
期刊：
MMWR. Morbidity and mortality weekly report
影响因子：
--
作者：
Boehmer TK;DeVies J;Caruso E;van Santen KL;Tang S;Black CL;Hartnett KP;Kite-Powell A;Dietz S;Lozier M;Gundlapalli AV
通讯作者：
Gundlapalli AV