Associations of educational attainment, occupation, and community poverty with hip osteoarthritis.

Associations of educational attainment, occupation, and community poverty with hip osteoarthritis.
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DOI:
10.1002/acr.21920
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发表时间:
2013-06
影响因子:
4.7
通讯作者:
Callahan, Leigh F.
Callahan, Leigh F.
中科院分区:
医学2区
文献类型:
--
作者:
Cleveland, Rebecca J.;Schwartz, Todd A.;Prizer, Lindsay P.;Randolph, Randy;Schoster, Britta;Renner, Jordan B.;Jordan, Joanne M.;Callahan, Leigh F.

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检查来自约翰斯顿县骨关节炎项目的横断面基线数据,以了解个人和社区社会经济地位(SES)测量与髋关节骨关节炎(OA)结果之间的关系。我们分析了3,087人的数据(68%的白人和32%的非洲裔美国人)。以受教育程度和职业作为SES的个体测量指标。人口普查分组家庭贫困率被用作衡量社区社会经济地位的指标。髋关节骨性关节炎的结果包括单侧或双侧髋关节的影像学骨性关节炎(rOA)和症状性骨性关节炎(sxOA)。使用多变量logistic回归模型分别估计每个髋部OA结局与每个SES变量之间的比值比(OR)和95%置信区间(CI),然后同时估计所有SES测量值。评估了种族和性别对髋关节炎结局和SES变量的影响。生活在家庭贫困率较高的社区与单侧或双侧髋关节rOA (or =1.50; 95% CI= 1.18-1.92)和双侧(双侧髋关节)rOA (or =1.87; 95% CI= 1.32-2.66)存在独立关联。在同时对所有SES测量进行调整后,发现单侧或双侧髋关节骨关节炎患者(or =1.44; 95% CI=1.09, 1.91)或双侧髋关节骨关节炎患者(or =1.91; 95% CI= 1.08-3.39)的受教育程度较低之间存在类似的独立关联。没有观察到职业和髋关节骨关节炎结局之间的显著关联,种族或性别也没有改变这种关联。我们的数据提供的证据表明,髋关节骨关节炎的结果与教育和社区社会经济状况指标相关,在调整协变量和所有社会经济状况指标后,这种关联仍然存在。
To examine cross-sectional baseline data from the Johnston County Osteoarthritis Project for the association between individual and community socioeconomic status (SES) measures with hip osteoarthritis (OA) outcomes. We analyzed data on 3,087 individuals (68% Caucasian and 32% African American). Educational attainment and occupation were used as individual measures of SES. Census block group household poverty rate was used as a measure of community SES. Hip OA outcomes included radiographic OA (rOA) and symptomatic OA (sxOA) in one or both hip joints. Multivariable logistic regression models were used to estimate odds ratios (OR) and 95% confidence intervals (CI) for the association of each hip OA outcome with each SES variable separately, then with all SES measures simultaneously. Associations between hip OA outcomes and SES variables were evaluated for effect modification by race and gender. Living in a community of high household poverty rate showed independent associations with hip rOA in one or both hips (OR=1.50; 95% CI=1.18–1.92) and bilateral (both hips) rOA (OR=1.87; 95% CI=1.32–2.66). Similar independent associations were found between low educational attainment among those with sxOA in one or both hips (OR=1.44; 95% CI=1.09, 1.91) or bilateral sxOA (OR=1.91; 95% CI=1.08–3.39), after adjusting for all SES measures simultaneously. No significant associations were observed between occupation and hip OA outcomes, nor did race or gender modify the associations. Our data provide evidence that hip OA outcomes are associated with both education and community SES measures, associations which remained after adjustment for covariates and all SES measures.
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