Adverse Childhood Experiences and Blood Pressure in Women in the United States: A Systematic Review.

Adverse Childhood Experiences and Blood Pressure in Women in the United States: A Systematic Review.
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DOI:
10.1111/jmwh.13213
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发表时间:
2021-01
期刊:
Journal of midwifery & women's health
影响因子:
--
通讯作者:
Simmons LA
Simmons LA
中科院分区:
其他
文献类型:
--
作者:
Scott J;McMillian-Bohler J;Johnson R;Simmons LA

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血压升高是导致心血管不良结局的主要因素。一些研究表明,不良童年经历(ACE)与成年后血压升高之间存在关联。具体到ACE和女性血压的文献还没有被合成,因此,本系统综述的目的是检查什么是已知的ACE和血压之间的关联在美国生活的女性。与医学图书馆员合作,对1998年1月至2019年12月期间发表的文献进行了系统检索。从PubMed、CINAHL和PsycINFO数据库中识别原始同行评审出版物。如果研究(1)在美国境外进行,(2)测量急性压力或成人压力源,或(3)测量儿童或妊娠相关结果,则将其排除在外。在1740篇文章中,12篇出版物符合本研究的入选标准,其中8篇来自队列研究。人种和种族多样性有限,本综述中的一半文章由大多数白色样本组成。在使用自我报告的高血压史的研究中,60%获得了与ACE的显著关联,而只有30%的研究有客观的血压数据。在3项研究中,ACE与低血压相关。需要更多的研究来阐明ACE和血压升高之间的关系。结果的增强可能与血压测量、ACE评估和人群特征有关。未来的研究应纳入不同的人群代表性样本,并考虑性别或种族特异性压力源,如怀孕或种族主义及其对血压的潜在影响。卫生保健提供者可能会考虑ACE的历史作为筛查女性患者心血管危险因素的一部分,特别是血压升高的年轻女性。
Elevated blood pressure is a leading contributor to adverse cardiovascular outcomes. Some studies suggest there is an association between adverse childhood experiences (ACEs) and subsequent elevated blood pressure in adulthood. The literature specific to ACEs and blood pressure in women has not been synthesized; thus the purpose of this systematic review was to examine what is known about the association between ACEs and blood pressure in women living in the United States. In collaboration with a medical librarian, a systematic search of the literature published between January 1998 and December 2019 was conducted. Original, peer-reviewed publications were identified from PubMed, CINAHL, and PsycINFO databases. Studies were excluded if they (1) were conducted outside the United States, (2) measured acute stress or adult stressors, or (3) measured childhood- or pregnancy-related outcomes. Of 1740 articles, 12 publications met criteria for inclusion in this study, 8 of which were from cohort studies. Racial and ethnic diversity was limited, with half of the articles in this review consisting of samples that were majority white. Of the studies that used a self-reported history of hypertension, 60% obtained significant associations with ACEs, compared with only 30% of the studies that had objective blood pressure data. ACEs were associated with lower blood pressure in 3 studies. More research is needed to elucidate the relationship between ACEs and elevated blood pressure. Inconsistencies in the findings may be related to the measurement of blood pressure, assessment of ACEs, and population characteristics. Future studies should incorporate diverse population-representative samples with consideration for sex- or race-specific stressors such as pregnancy or racism and their potential influence on blood pressure. Health care providers may consider the history of ACEs as part of screening for cardiovascular risk factors among female patients, especially younger women presenting with elevated blood pressure.
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