Identification of the neural pathway for reinforcement of feeding when Aplysia learn that food is inedible
Identification of the neural pathway for reinforcement of feeding when Aplysia learn that food is inedible
复制标题
当海兔得知食物不可食用时强化摄食的神经通路的识别
DOI：
10.1523/jneurosci.06-05-01528.1986
复制
发表时间：
1986
影响因子：
4.7
通讯作者：
Abraham J Susswein
中科院分区：
文献类型：
--
作者：
M. Schwarz;Abraham J Susswein
双侧切断支配海兔肠道的食道神经被发现对不能进食的食物的反应减少有深刻的影响：停止进食的时间延长，训练24小时后没有关于减少的记忆，训练时的运动模式发生了改变。观察对持续嘴唇刺激反应减退的参数特征，以确定它们与食道神经切断后对不可食用食物的反应减退参数的相似性。反应减退的参数相似，表明食道神经切断后反应减退可能是持续嘴唇刺激的结果。双侧神经切断对持续的嘴唇刺激所致的减少没有影响。单侧损伤和损伤食道神经的两个主要分支中的任何一个都没有影响到学习食物是不能吃的。数据表明，双侧神经切断消除了由于不能进食而导致负强化进食的所有刺激。基于这篇论文和前一篇论文中的数据，提出了一个模型，提出了在海兔中学习食物可食用或不可食用的作用地点和机制。
Bilateral sectioning of the esophageal nerves that innervate the gut of Aplysia was found to have profound effect on response decrement to inedible food: Time to criterion for cessation of feeding was elevated, no memory of the decrement was present 24 hr after training, and motor patterning during training was altered. The parametric features of response decrement to sustained lip stimulation were examined to determine their resemblance to parameters of response decrement to inedible food after esophageal nerve sectioning. Parameters of response decrement were similar, indicating that after esophageal nerve sectioning response decrement is likely to be the result of sustained lip stimulation. Bilateral nerve sectioning had no effect on decrement due to sustained lip stimulation. Unilateral lesions and lesions of either of the two major divisions of the esophageal nerves had no effect on learning that food was inedible. The data indicate that bilateral nerve sectioning eliminates all stimuli causing negative reinforcement of feeding due to failure to consume food. Based on the data in this and the previous paper, a model is presented suggesting sites of action and mechanisms for learning that foods are edible or inedible in Aplysia.
内部刺激增强了软体动物海兔的摄食行为。
DOI：
10.1016/s0163-1047(84)90784-2
发表时间：
1984
期刊：
Behavioral and neural biology
影响因子：
--
作者：
Susswein,AJ;Weiss,KR;Kupfermann,I
通讯作者：
Kupfermann,I
单个感觉神经元的联想调节暗示了学习的细胞机制。
DOI：
10.1126/science.6294834
发表时间：
1983
期刊：
Science (New York, N.Y.)
影响因子：
--
作者：
Walters,ET;Byrne,JH
通讯作者：
Byrne,JH
影响因子：
56.9
作者：
KANDEL, ER;SCHWARTZ, JH
通讯作者：
SCHWARTZ, JH