Disturbed subjective sleep characteristics in adult patients with long-standing type 1 diabetes mellitus.
Disturbed subjective sleep characteristics in adult patients with long-standing type 1 diabetes mellitus.
复制标题
DOI：
10.1007/s00125-011-2184-7
复制
发表时间：
2011-08
期刊：
影响因子：
8.2
通讯作者：
Romijn, J. A.
中科院分区：
文献类型：
--
作者：
van Dijk, M.;Donga, E.;van Dijk, J. G.;Lammers, G. J.;van Kralingen, K. W.;Dekkers, O. M.;Corssmit, E. P. M.;Romijn, J. A.
睡眠时间缩短和/或睡眠质量受损会对血糖调节产生负面影响。本研究的目的是评估 1 型糖尿病患者的主观睡眠特征，将睡眠特征与长期血糖控制联系起来，并评估睡眠受损的可能危险因素。我们研究了 99 名成年 1 型糖尿病患者（55 名男性，44 名女性，糖尿病病程 26.9±1.2 年）和 99 名年龄、性别和 BMI 匹配的非糖尿病对照者。主观睡眠特征通过经过验证的问卷进行评估，即匹兹堡睡眠质量指数、爱普沃斯嗜睡量表和柏林问卷。通过 HbA1c 值评估血糖调节。临床变量从医学图表中获得。抑郁症通过医院焦虑和抑郁量表（HADS）进行评估。通过神经学检查和定量感觉测试来评估周围性多发性神经病。在 1 型糖尿病患者中，35% 的患者主观睡眠质量较差，而对照组参与者的这一比例为 20% (p = 0.021)。较高比例的 1 型糖尿病患者罹患阻塞性睡眠呼吸暂停 (OSA) 的风险较高（17.2% vs 5.1%，p = 0.012）。个体睡眠特征与 HbA1c 值之间没有显着关联。在逻辑回归分析中，HADS 抑郁评分、周围性多发性神经病、习惯性打鼾和其他睡眠障碍（例如低血糖）与睡眠质量差独立相关。与对照参与者相比，长期患有 1 型糖尿病的成年患者主观睡眠质量受到干扰，并且 OSA 的风险更高。主观睡眠障碍是长期 1 型糖尿病复杂综合征的一部分。
Decreased sleep duration and/or impaired sleep quality negatively influence glucoregulation. The aim of this study was to assess subjective sleep characteristics in patients with type 1 diabetes, to relate sleep characteristics to long-term glycaemic control and to assess possible risk factors for impaired sleep. We studied 99 adult patients with type 1 diabetes (55 men, 44 women, duration of diabetes 26.9 ± 1.2 years) and 99 age-, sex- and BMI-matched non-diabetic controls. Subjective sleep characteristics were assessed by validated questionnaires, i.e. Pittsburgh Sleep Quality Index, Epworth Sleepiness Scale and the Berlin Questionnaire. Glucoregulation was assessed by HbA1c values. Clinical variables were obtained from medical charts. Depression was assessed by the Hospital Anxiety and Depression Scale (HADS). Peripheral polyneuropathy was assessed by neurological examination and quantitative sensory testing. Of the patients with type 1 diabetes, 35% had subjective poor sleep quality compared with 20% of the control participants (p = 0.021). A higher proportion of the patients with type 1 diabetes were at increased risk for obstructive sleep apnoea (OSA) (17.2% vs 5.1%, p = 0.012). There was no significant association between individual sleep characteristics and HbA1c values. On logistic regression analysis, the HADS depression score, presence of peripheral polyneuropathy, habitual snoring and other sleep disturbances (e.g. hypoglycaemia) were independently associated with poor sleep quality. Adult patients with long-standing type 1 diabetes mellitus have disturbed subjective sleep quality and a higher risk for OSA compared with control participants. Subjective sleep disturbances are part of the complex syndrome of long-standing type 1 diabetes.
登录
查看更多内容
影响因子：
--
作者：
Paranjape, Sachin A.;Vavaiya, Karnlesh K.;Briski, Karen P.
通讯作者：
Briski, Karen P.
影响因子：
5.1
作者：
Matyka, KA;Crawford, C;Stores, G
通讯作者：
Stores, G
影响因子：
5
作者：
Punjabi, NM;Shahar, E;Resnick, HE
通讯作者：
Resnick, HE
影响因子：
16.2
作者：
Ayas, NT;White, DP;Hu, FB
通讯作者：
Hu, FB
影响因子：
16.2
作者：
Rutkove SB;Veves A;Mitsa T;Nie R;Fogerson PM;Garmirian LP;Nardin RA
通讯作者：
Nardin RA