Potential Causes of Titanium Particle and Ion Release in Implant Dentistry: A Systematic Review.
Potential Causes of Titanium Particle and Ion Release in Implant Dentistry: A Systematic Review.
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DOI：
10.3390/ijms19113585
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发表时间：
2018-11-13
影响因子：
5.6
通讯作者：
Romanos G
中科院分区：
文献类型：
--
作者：
Delgado-Ruiz R;Romanos G
种植体表面特性以及物理和机械特性是牙种植体、骨和周围软组织之间积极相互作用的原因。不幸的是，牙种植体表面不会保持不变，并且在种植体的寿命期间会随着时间而变化。如果种植体表面发生变化，可能引发粘膜炎和种植体周围炎过程;种植体骨整合可能被破坏，骨吸收现象（骨质溶解）可能导致种植体丢失。本系统综述收集了与牙科种植中钛颗粒和离子的潜在来源相关的信息。研究问题的结构在人口，干预，比较，结果（皮科）框架。开发了皮科问卷，并对1980年至2018年期间发表的所有相关研究进行了详尽检索，这些研究涉及与牙科种植体手术相关的钛颗粒和离子。在本综述中选择和纳入手稿时，遵循了系统性综述和荟萃分析的首选报告项目（PRISMA）指南。钛颗粒和离子在植入床准备、植入物插入和植入物去污过程中释放。此外，植入物表面和涂层暴露于唾液、细菌和化学物质，这些物质可能会溶解氧化钛层，因此可能会引发腐蚀循环。机械因素、微间隙和氟化物也会影响植入物和植入物释放的金属颗粒和离子的比例。
Implant surface characteristics, as well as physical and mechanical properties, are responsible for the positive interaction between the dental implant, the bone and the surrounding soft tissues. Unfortunately, the dental implant surface does not remain unaltered and changes over time during the life of the implant. If changes occur at the implant surface, mucositis and peri-implantitis processes could be initiated; implant osseointegration might be disrupted and bone resorption phenomena (osteolysis) may lead to implant loss. This systematic review compiled the information related to the potential sources of titanium particle and ions in implant dentistry. Research questions were structured in the Population, Intervention, Comparison, Outcome (PICO) framework. PICO questionnaires were developed and an exhaustive search was performed for all the relevant studies published between 1980 and 2018 involving titanium particles and ions related to implant dentistry procedures. Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines were followed for the selection and inclusion of the manuscripts in this review. Titanium particle and ions are released during the implant bed preparation, during the implant insertion and during the implant decontamination. In addition, the implant surfaces and restorations are exposed to the saliva, bacteria and chemicals that can potentially dissolve the titanium oxide layer and, therefore, corrosion cycles can be initiated. Mechanical factors, the micro-gap and fluorides can also influence the proportion of metal particles and ions released from implants and restorations.
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通讯作者：
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