Viruses in the faecal microbiota of monozygotic twins and their mothers.
Viruses in the faecal microbiota of monozygotic twins and their mothers.
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作者：
Viral diversity and lifecycles are poorly understood in the human gut and other body habitats. Therefore, we sequenced the viromes (metagenomes) of virus-like particles isolated from fecal samples collected from adult female monozygotic twins and their mothers at three time points over a one-year period. These datasets were compared to datasets of sequenced bacterial 16S rRNA genes and total fecal community DNA. Co-twins and their mothers share a significantly greater degree of similarity in their fecal bacterial communities than do unrelated individuals. In contrast, viromes are unique to individuals regardless of their degree of genetic relatedness. Despite remarkable interpersonal variations in viromes and their encoded functions, intrapersonal diversity is very low, with >95% of virotypes retained over the period surveyed, and with viromes dominated by a few temperate phage that exhibit remarkable genetic stability. These results indicate that a predatory viral-microbial dynamic, manifest in a number of other characterized environmental ecosystems, is notably absent in the very distal intestine.
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影响因子：
14.9
作者：
Jensen LJ;Kuhn M;Stark M;Chaffron S;Creevey C;Muller J;Doerks T;Julien P;Roth A;Simonovic M;Bork P;von Mering C
通讯作者：
von Mering C
影响因子：
14.9
作者：
Grissa, Ibtissem;Vergnaud, Gilles;Pourcel, Christine
通讯作者：
Pourcel, Christine
影响因子：
6.6
作者：
Gon, Stephanie;Faulkner, Melinda J.;Beckwith, Jon
通讯作者：
Beckwith, Jon
人腹泻的宏基因组分析：病毒检测和发现。
影响因子：
6.7
作者：
Finkbeiner, Stacy R.;Allred, Adam F.;Tarr, Phillip I.;Klein, Eileen J.;Kirkwood, Carl D.;Wang, David
通讯作者：
Wang, David
DOI：
10.1006/bbrc.1996.1778
发表时间：
1996-12-04
影响因子：
3.1
作者：
Garriga, X;Eliasson, R;Reichard, P
通讯作者：
Reichard, P