Comparative analysis of bacterial essential and nonessential genes with Hurst exponent based on chaos game representation
Comparative analysis of bacterial essential and nonessential genes with Hurst exponent based on chaos game representation
复制标题
基于混沌博弈表示的细菌必需和非必需基因与Hurst指数的比较分析
DOI:
10.1016/j.chaos.2014.10.003
复制
发表时间:
2014-12
影响因子:
7.8
通讯作者:
Yong-Ming Yu
中科院分区:
文献类型:
--
作者:
Qian Zhou;Yong-Ming Yu
Essential genes are indispensable for the survival of an organism. Investigating features associated with gene essentiality is fundamental to the prediction and identification of essential genes with computational techniques. We use fractal theory approach to make comparative analysis of essential and nonessential genes in bacteria. The Hurst exponents of essential genes and nonessential genes available in the DEG database for 27 bacteria are calculated based on their gene chaos game representations. It is found that for most analyzed bacteria, weak negative correlation exists between Hurst exponent and gene length. Moreover, essential genes generally differ from nonessential genes in their Hurst exponent. For genes of similar length, the average Hurst exponent of essential genes is smaller than that of nonessential genes. The results of our work reveal that gene Hurst exponent is very probably useful gene feature for the algorithm predicting essential genes.
登录
查看更多内容
影响因子:
7.8
作者:
Zhi-Yuan Su;Tzuyin Wu;Shu-Yin Wang
通讯作者:
Zhi-Yuan Su;Tzuyin Wu;Shu-Yin Wang
影响因子:
3.7
作者:
Gao F;Zhang RR
通讯作者:
Zhang RR
影响因子:
14.9
作者:
Luo H;Lin Y;Gao F;Zhang CT;Zhang R
通讯作者:
Zhang R
影响因子:
2
作者:
Wang, Zhen;Szolnoki, Attila;Perc, Matjaz
通讯作者:
Perc, Matjaz
影响因子:
56.9
作者:
KARLIN, S;BRENDEL, V
通讯作者:
BRENDEL, V