Probing Posttranslational Redox Modifications.
Probing Posttranslational Redox Modifications.
复制标题
探测翻译后氧化还原修饰
DOI:
10.1007/978-1-4939-7136-7_12
复制
发表时间:
2017
影响因子:
--
通讯作者:
Dietz KJ
中科院分区:
文献类型:
--
作者:
Treffon P;Liebthal M;Telman W;Dietz KJ
Reactive molecular species (RMS) can damage DNA, lipids, and proteins but as signaling molecules they also affect the regulatory state of the cell. RMS consist of reactive oxygen (ROS), nitrogen (RNS), and carbonyl species (RCS). Besides their potentially destructive nature, RMS are able to modify proteins at the posttranslational level, resulting in regulation of structure, activity, interaction as well as localization. This chapter addresses methods to analyze and quantify posttranslational redox modifications in vitro and ex vivo, such as sulfenic acid generation of cysteine residues and oxidative carbonylation of proteins. In addition, by use of isothermal titration calorimetry, redox-dependent interaction studies of proteins will be described.
登录
查看更多内容
DOI:
10.1016/j.bbapap.2016.01.005
发表时间:
2016
期刊:
Biochimica et biophysica acta
影响因子:
--
作者:
Mock HP;Dietz KJ
通讯作者:
Dietz KJ
影响因子:
2.9
作者:
Barranco-Medina, Sergio;Kakorin, Sergej;Dietz, Karl-Josef
通讯作者:
Dietz, Karl-Josef
影响因子:
4.9
作者:
Liebthal, Michael;Strueve, Marcel;Dietz, Karl-Josef
通讯作者:
Dietz, Karl-Josef
DOI:
10.1016/j.bbagen.2013.05.040
发表时间:
2014-02
期刊:
Biochimica et biophysica acta
影响因子:
--
作者:
Gupta V;Carroll KS
通讯作者:
Carroll KS
影响因子:
2.9
作者:
Todd, MJ;Gomez, J
通讯作者:
Gomez, J