Conjoint activity of anterior insular and anterior cingulate cortex: awareness and response.

Conjoint activity of anterior insular and anterior cingulate cortex: awareness and response.
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DOI:
10.1007/s00429-010-0265-x
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发表时间:
2010-06
影响因子:
3.1
通讯作者:
Critchley, Hugo D.
Critchley, Hugo D.
中科院分区:
医学3区
文献类型:
--
作者:
Medford, Nick;Critchley, Hugo D.

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现在有大量的证据表明,前岛叶和前扣带皮层有着密切的功能关系,因此它们可以一起被认为是功能系统的输入和输出区域。这个系统通常涉及认知,情感和行为环境,这表明它对心理生活至关重要。在这里,我们回顾了文献,并强调这些大脑区域是至关重要的情况下,首先,生产的主观感受,其次,协调适当的反应,内部和外部事件。该模型试图将高阶皮层功能与感觉表征和自主控制相结合:有人认为感觉状态来自感觉(包括内感受)输入的原始数据,并通过有意识意识的表征进行整合。相应地,自主神经系统的反应在伴随意识体验的反应中尤为重要。还讨论了潜在的临床意义。
There is now a wealth of evidence that anterior insular and anterior cingulate cortices have a close functional relationship, such that they may be considered together as input and output regions of a functional system. This system is typically engaged across cognitive, affective, and behavioural contexts, suggesting that it is of fundamental importance for mental life. Here, we review the literature and reinforce the case that these brain regions are crucial, firstly, for the production of subjective feelings and, secondly, for co-ordinating appropriate responses to internal and external events. This model seeks to integrate higher-order cortical functions with sensory representation and autonomic control: it is argued that feeling states emerge from the raw data of sensory (including interoceptive) inputs and are integrated through representations in conscious awareness. Correspondingly, autonomic nervous system reactivity is particularly important amongst the responses that accompany conscious experiences. Potential clinical implications are also discussed.
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影响因子: 4.5
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