Variable selection method for quantitative trait analysis based on parallel genetic algorithm.
Variable selection method for quantitative trait analysis based on parallel genetic algorithm.
复制标题
基于并行遗传算法的数量性状分析变量选择方法
DOI:
10.1111/j.1469-1809.2009.00548.x
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发表时间:
2010
影响因子:
1.9
通讯作者:
Xu,Hongyan
中科院分区:
文献类型:
--
作者:
Mukhopadhyay,Siuli;George,Varghese;Xu,Hongyan
Selection of important genetic and environmental factors is of strong interest in quantitative trait analyses. In this study, we use parallel genetic algorithm (PGA) to identify genetic and environmental factors in genetic association studies of complex human diseases. Our method can take account of both multiple markers across the genome and environmental factors, and also can be used to do fine mapping based on the results of haplotype analysis to select the markers that are associated with the quantitative traits. Using both simulated and real examples, we show that PGA is able to choose the variables correctly and is also an easy‐to‐use variable selection tool.
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影响因子:
3.7
作者:
Utsunomiya YT;Pérez O'Brien AM;Sonstegard TS;Van Tassell CP;do Carmo AS;Mészáros G;Sölkner J;Garcia JF
通讯作者:
Garcia JF
DOI:
--
发表时间:
1993
期刊:
Genetical research
影响因子:
--
作者:
P. Keightley;Grahame Bulfield
通讯作者:
Grahame Bulfield
影响因子:
3
作者:
Carvajal-Rodríguez A
通讯作者:
Carvajal-Rodríguez A
影响因子:
4.5
作者:
Comeron JM;Ratnappan R;Bailin S
通讯作者:
Bailin S
影响因子:
5.8
作者:
Lambert, Brian W.;Terwilliger, Joseph D.;Weiss, Kenneth M.
通讯作者:
Weiss, Kenneth M.