BamToCov: an efficient toolkit for sequence coverage calculations.
BamToCov: an efficient toolkit for sequence coverage calculations.
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DOI:
10.1093/bioinformatics/btac125
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发表时间:
2022-04-28
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Many genomics applications require the computation of nucleotide coverage of a reference genome or the ability to determine how many reads map to a reference region. BamToCov is a toolkit for rapid and flexible coverage computation that relies on the most memory efficient algorithm and is designed for integration in pipelines, given its ability to read alignment files from streams. The tools in the suite can process sorted BAM or CRAM files, allowing the user to extract coverage information via different filtering approaches and to save the output in different formats (BED, Wig or counts). The BamToCov algorithm can also handle strand-specific and/or physical coverage analyses. This program, accessory utilities and their documentation are freely available at https://github.com/telatin/BamToCov. Supplementary data are available at Bioinformatics online.
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作者:
Quinlan, Aaron R
通讯作者:
Quinlan, Aaron R
DOI:
10.1093/bioinformatics/btx699
发表时间:
2018-03-01
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Bioinformatics (Oxford, England)
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作者:
Pedersen BS;Quinlan AR
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Quinlan AR
DOI:
10.1093/bioinformatics/btp324
发表时间:
2009-07-15
期刊:
Bioinformatics (Oxford, England)
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作者:
Li H;Durbin R
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Durbin R
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9.2
作者:
Bonfield JK;Marshall J;Danecek P;Li H;Ohan V;Whitwham A;Keane T;Davies RM
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Davies RM
DOI:
10.1093/bioinformatics/btv098
发表时间:
2015-06-15
期刊:
Bioinformatics (Oxford, England)
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作者:
Tarasov A;Vilella AJ;Cuppen E;Nijman IJ;Prins P
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Prins P