Vitamin supplementation in the treatment of schizophrenia.
Vitamin supplementation in the treatment of schizophrenia.
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DOI：
10.1007/s40263-014-0172-4
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发表时间：
2014-07
期刊：
影响因子：
6
通讯作者：
Roffman, Joshua L.
中科院分区：
文献类型：
--
作者：
Brown, Hannah E.;Roffman, Joshua L.
In this article we review the current literature addressing the treatment of schizophrenia with vitamin supplementation. We first describe the important roles that vitamins play in normal metabolism, then review the evidence pertaining to vitamin deficiency and supplementation in patients with schizophrenia. We then describe mounting evidence suggesting that vitamin supplementation, in particular with folic acid, vitamin B12 and vitamin D, may be important in treatment within certain subgroups of patients. We highlight the need for larger, randomized controlled trials, and recommend further studies examining the incidence of schizophrenia in countries with poor prenatal care and malnutrition, as well as in countries that have adopted mandatory folic acid fortification of grain products.
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